Okay, let's wrap up this group of meds.
There are some potentially life-
threatening adverse effects,
and I want to make sure that
you didn't miss them.
Now, C. diff associated diarrhea
can cause some
major problems because you have
issues with fluid volume loss.
Now, anytime you have diarrhea,
you have more water leaving
the body than should be
because the waste is going
through the body so quick.
It's meant to go through the gut slowly,
so you're having more water leave
the body than should be.
That means your patient is at increased
risk for low blood pressure,
hypotensive, and risk for falls.
So, you want to watch someone very
closely who has C. diff diarrhea,
because we're going to really have
a problem with hypotension,
risk for falls, because of that low blood
pressure, they'll get really dizzy.
So the meds that can cause C. diff
associated diarrhea, besides
being really stinky, if I haven't
made that point clear yet,
are clindamycin and tetracyclines.
Torsades de point is that life-threatening
You want to remember that's an issue
with the macrolides, erythromycin.
Liver damage or hepatotoxicity,
that can be caused by tetracyclines
Renal toxicity, nephrotoxicity
or damage to the kidneys can be
caused by the tetracyclines.
Now, remember that it's reversible, but you
can have that bone marrow suppression,
myelosuppression, of the white cells, the
red cells, the platelets, or all of them.
That can happen.
Now, this family of drugs can mess
with some super bugs
and that's really good, so
we've got some tools
in our tool belt to deal with them.
For MRSA, you can use linezolid.
That's remember, methicillin-resistant
The treatment of VRE, vancomycin-
is linezolid and dalfopristin/quinupristin.
So, this slide is really important.
Do whatever you do in your
notes to highlight that,
but it's important, as a nurse
and as a nursing student,
that you keep in mind
that these medications should only be used
for very serious infections,
so we don't make the same mistakes
that we've made in the past.
Thank you for watching our video
on this family of antibiotics.