So let's wrap up this video series.
Neuromuscular blockers cause extreme
skeletal relaxation or paralysis,
including the diaphragm.
Patients on NMB's
require ventilator support
or mechanical ventilation because
that skeletal muscle of diaphragm
and they can't breathe on their own.
compete with acetylcholine
for the nicotinic M receptors.
That patient is completely paralyzed
but fully conscious.
Sedative should always be given
for neuromuscular blockers.
And succinylcholine is often used
in surgery for intubations.
Now, the possible adverse effect
are increased potassium,
postoperative muscle pain
and the most life threatening one of