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Now, which drugs don't play well with succs? Well, you're going to watch for a more intense
effect of succinylcholine if the patient is on a cholinesterase inhibitor. Now, before I break
that down, I want you to think through, just pause and think what is cholinesterase based on
its name an inhibitor. So, see if you can figure out what this does. Okay, I hope you took
advantage of pausing the video and stopping to think because you'll be amazed at yourself
at how much you already know. We see it's a-s-e. We know that's an enzyme. We know that
enzymes break down things, and then we know that before that is choline, so this is an enzyme
that breaks down choline, but this is a cholinesterase inhibitor so that means it's going to
block the action of cholinesterase, this enzyme that breaks down choline, so I'm going to have
extra. Right? I'm going to have a more intense effect. That's why it potentiates the effects of
succinylcholine. So, if someone is taking succinylcholine but they're already on a cholinesterase
inhibitor for some other problem, this means that succs is going to be supercharged and
powerful. There are also some antibiotics. I've listed them for you, but they can also mess with
the intensity of succinylcholine. So, keep that in mind. This is why a history is over important
with every patient especially this is an elective procedure. That's why multiple people ask the
same questions multiple times. They know they're going to give this drug. These are the things
that they're going to look at when they're assessing that patient.