Corticosteroids and cyclophosphamide.
Subendothelial deposits is what we're looking at here on electron microscopy.
Same thing, get in the habit of doing this quickly.
The more number of times you go to the protocol the better off you’ll be.
You’ll find your glomerular basement membrane paved road.
Number two, you look for the foot processes.
Well, there’s nothing underneath the foot process because this is DPGN.
Which gives you what? The title of the slide is subendothelial.
So therefore, you would find this underneath the endothelial cell.
Thin rim of normal basement membrane,
it separates the epithelial side from the obviously the endothelial side.
Patient has diffused proliferative glomerulonephritis
and as we talked about the prototype here, will be SLE.
If you pay attention, this is your electron microscopy with subendothelial DPGN.
As you see here on light microscopy, there’s going to be diffused proliferation.
There is going to be hypercellularity and there’s neutrophils within the mesangium.
What’s your mesangium?
Basically, think of it as being the supportive infrastructure of your glomerulus,
which then properly support your glomerular capillaries and all.
Also, it very much behaves like smooth muscle in which it will contract when need be.