Now, one last example is a psych medication.
So, I want you to be familiar
with this type of concept
because this gets a little more complicated
in your central nervous system.
We’re going to talk about
and a really common group that’s
prescribed in the United States
Now, that’s Selective Serotonin
Now you know why we call them SSRIs,
but the generic name is fluoxetine
or you may have heard it called
It’s been around for a really long time.
So, take a look at this drawing:
they’ve got the presynaptic nerve ending
and the postsynaptic nerve ending.
Now, all of the little keys in there
and serotonin is a neurotransmitter
that makes you feel good,
so if I’m suffering from depression,
the more serotonin I can have
available to my brain,
the better I’m going to feel.
So, you see that we have some
little keys and some little trucks
that represents the serotonin.
Now, some of the keys are tucked
into that postsynaptic nerve
and that’s when you feel good
and they’re being used.
Presynaptically, you see that we
have some smaller keys.
That’s the serotonin that’s being
used and has been reuptook.
What’s a better way to say that?
But, the process is they’ve taken it
back up into the nerve ending
once it’s been used and it’s done its job.
So, we have the little trucks that
represent the transporters.
Now, here’s how we work with treating
depression with SSRIs.
The idea is if we block the
reuptake of the serotonin,
there will be more serotonin available.
So, you see in the next picture,
the drug acts like that giant STOP sign.
It blocks the reuptake of serotonin—
that’s how they get their name—
selective serotonin reuptake inhibitors.
Through that process, I have
more serotonin available
and, therefore, I have the ability
to try and treat that depression
and to feel better.
And that’s straightforward how
the reuptake inhibitors work.
Now, every person is a little different,
and as we just talked about depression,
I really want to underscore and
to emphasize for you
that depression is not a simple
treatment plan sometimes
and if you have sought a physician
or a healthcare provider’s
advice or prescriptions, and
it’s not working for you,
please go see someone else,
go for a second opinion,
and continue to try some options.
We’ll talk more about the psych meds,
but that’s a very serious challenge—
and I want to make sure that
we can treat it effectively
but sometimes it just takes a while
to get to the right appropriate medication,
because every person is different.
We all have variations, we have
and nurses need to know what the
expected pharmacodynamics are
and we can help problem solve when
something is different in our patients.
So, what are the things you need to do to
be aware of and to kind of problem solve,
be proactive about the
and keeping your patients safe?
Well, it’s all back to the nursing process.
You want to make sure that you’re
accurately assessing that patient
that you’re planning on the next best step,
that you’re implementing that plan and
evaluating that plan to make sure
that the benefits the patient is receiving
outweigh any safety concerns
that you might have.
So, thank you for watching this
video on pharmacodynamics.
I know it may have sounded like,
“Why in the world will I need to know this?”
But, I hope now you have a
of why it’s so important to
keep our patients safe
through a basic understanding and
application of pharmacodynamics.