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Sedative Drugs – Opiates and Sedatives

by Brian Warriner, MD

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    00:00 So let's talk a little bit about some of the other drugs.

    00:02 The most effective anti-anxiety medications we have are benzodiazepines. These are drugs such as, Valium is the one that people remember, that's an older drug. Currently we use midazolam and lorazepam primarily.

    00:20 We used to use these drugs as part of a pre-med, before the patient came to surgery, an hour or two before surgery. But this is largely been abandoned much to everyone's surprise. Patients found the sedation and the often accompanying amnesia associated with these drugs, to be unpleasant.

    00:38 With very anxious patients, a drug such as midazolam, will bring some relief prior to induction of anesthesia. Plus the amnestic effect usually associated with the medication may reduce the possibility of recall during anesthesia.

    00:56 These agents are generally utilized as sleep aids or anti-anxiety medications, and are not widely used for patients who are going to receive general anesthesia.

    01:08 They are very effective however improving anxiety levels when patients are undergoing regional anesthesia or surgery under local anesthetic injection.


    About the Lecture

    The lecture Sedative Drugs – Opiates and Sedatives by Brian Warriner, MD is from the course Anesthesiology: Introduction.


    Included Quiz Questions

    1. They are generally used in neuraxial blocks or regional blocks.
    2. They are effective amnestics in anesthesia.
    3. They comprise amide and phenolic forms.
    4. They block only the pain nerves.
    5. They can only be give intravenously.
    1. Benzodiazepines are no longer a preference for preoperative use in patients receiving general anesthesia.
    2. Benzodiazepines are not very effective as sleep aids.
    3. Benzodiazepines are not effective in improving anxiety levels of patients receiving regional anesthesia.
    4. Benzodiazepines contain a chemical substance called PABA.
    5. Benzodiazepines are the second most effective drugs in improving anxiety levels.
    1. Bupivacaine
    2. Cocaine
    3. Procaine
    4. Tetracaine
    5. Benzocaine

    Author of lecture Sedative Drugs – Opiates and Sedatives

     Brian Warriner, MD

    Brian Warriner, MD


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