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RNA Interference

by Kevin Ahern, PhD
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    About the Lecture

    The lecture RNA Interference by Kevin Ahern, PhD is from the course RNA and the Genetic Code.


    Included Quiz Questions

    1. It relies on formation of duplex RNA sequences in cells
    2. It occurs when transcription of a gene is blocked
    3. It involves pairing of a target RNA to a complementary sequence by a protein called dicer
    4. It arises when the RISC protein destroys an RNA duplex
    1. Dicer
    2. RNAse
    3. DNAse
    4. Protease
    5. Ligase
    1. The siRNA contains a mismatched duplex with a bulge on it, whereas the miRNA represents a perfect duplex system
    2. The presence of double-stranded RNA molecules in the eukaryotic cells stimulates the RNAi response
    3. The RNAi response helps the cell to protect itself from the invader as well as to control its own gene expressions
    4. The double-stranded viral RNA gets chopped off by enzyme called dicer into silencing RNA molecules of 20 basepair lengths
    5. Drosha and Dicer are two enzymes, which participate in the RNA interference process in the eukaryotic cells
    1. Argonaute, due to which it cleaves the target mRNA
    2. Dicer, due to which it cleaves the pri-miRNA
    3. Drosha, due to which it cleaves the pri-siRNA
    4. Drosha-dicer, due to which it cleaves the pri-viral RNA
    5. Lyase, due to which it cleaves the pri-mRNA

    Author of lecture RNA Interference

     Kevin Ahern, PhD

    Kevin Ahern, PhD


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