Hi, welcome to our video
series on interpreting lab values.
In this one, we're gonna dig much deeper
into the causes of abnormal levels of BUN
and what you should do about it
- those are the key interventions.
Now a quick review, remember
urea and renal function.
Urea is water-soluble, it contains
nitrogen and it's a waste product.
Now how we end up with it is the liver breaks down
protein, you end up with ammonia from that process,
so your liver transforms that into
urea and sends that it to your kidneys.
Now when urea arrives at your kidneys, it's normally filtered
by the healthy kidneys from the blood into the urine.
Normal levels are 7-20 (mg/dL).
If you're getting above 20 (mg/dL),
that's where we've got a problem,
either organ dysfunction -
look we've got liver or renal,
excess protein which could be from upper GI
bleeding or a high protein intake in your diet.
And thirdly, significant dehydration
can also cause an elevated BUN.