00:02
Students often have an issue with figuring out
the various pathologies because they dive right
into the lesions without really understanding
renal clinical anatomy. So in this lecture
series, initially we will be laying down the
foundation as to which you need to take a
look at. For example, you have heard of subepithelial,
subendothelial deposits, but once again you
will perhaps memorize that and at some point of
time, you will be asked on electron microscopy
how to identify. It is important that
we lay down the foundation, in this first set
of lectures so that as we move towards into
glomerulonephritis and tubular interstitial
disease, everything makes a lot more sense.
Let us begin. We had seen this picture before
and the reason we had was we were referring
to secondary hypertension when dealing renal
artery stenosis. Well, that was a beautiful
discussion at the time. Let us now move into
what we need to know here in the glomerular
pathology. The glomerulus, I want you to come
down the afferent arteriole and then as you
do so, you are coming into the tuft of capillaries
versus glomerular tuft or we will be spending
a lot of time in that area and in fact, we
will be blowing it up, amplifying it and then
go through various imaging studies that is
relevant for your diagnosis of your patient.
What are the different things that are taking
place in the tuft capillaries is what is relevant
and our next logical question.