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The lecture Regulation of Iron Transport by Kevin Ahern, PhD is from the course Amino Acid Metabolism.
Included Quiz Questions
Which of the following is true regarding the iron response element (IRE)?
- It is bound by the IRE-BP when iron concentration is low
- It is a protein
- It binds to iron when the iron concentration is high
- All of the answers are true
- None of the answers are true
Which is true regarding the binding of the IRE-BP to the IRE?
- It occurs when iron levels are low
- It favors translation of ferritin
- It occurs near the 3’ end of the ferritin mRNA
- All of the answers are true
- None of the answers are true
Which is true regarding the binding of the IRE-BP to the transferrin receptor mRNA?
- It occurs at the 3’ end
- It protects the 5’ end from nuclease degradation
- It reduces the synthesis of the receptor
- None of the answers are true
- All of the answers are true
What happens to ferritin regulation at the low levels of iron inside the cell?
- The IRE-BP binds to the IRE of the ferritin mRNA and halts the synthesis of the ferritin protein
- The IRE-BP binds to the iron and halts the synthesis of ferritin protein
- The IRE-BP binds to the iron and facilitates the synthesis of the ferritin protein
- The IRE-BP binds to the iron and facilitates the binding of iron with the ferritin mRNA
- The IRE-BP binds to the IRE of the ferritin mRNA and facilitates the synthesis of ferritin protein
How do the high concentrations of iron regulate the transferrin receptor protein synthesis?
- At high concentrations of iron, the binding of IRE-BP to iron makes transferrin mRNA susceptible to nuclease attack and prevent transferrin receptor protein synthesis
- At high concentrations of iron, the binding of IRE-BP to transferrin mRNA facilitates transferrin receptor protein synthesis
- At high concentrations of iron, the binding of iron to IRE of transferrin receptor mRNA facilitates the synthesis of transferrin receptor protein
- At high concentrations of iron, the binding of IRE-BP to iron and IRE of mRNA facilitates the synthesis of transferrin receptor protein
- At high concentrations of iron, the binding of IRE-BP to iron facilitates the synthesis of transferrin receptor protein
Author of lecture Regulation of Iron Transport
Kevin Ahern, PhD
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this guy so good only amazing so much only omg nice nice