00:01
Okay, so we talked about
neonates and infants,
let's move on to children
1 year of age or older.
00:07
This is my favorite age group.
00:09
I love this 1-year plus age when
they walk like Frankenstein,
they're so fun to be with.
00:15
Now, you're talking
about pharmacokinetics.
00:16
You already know that's absorption,
distribution, and excretion,
but whoa! Wait a minute,
we're missing one.
00:23
Well, there's a reason metabolism
is at the bottom of the slide.
00:26
See, absorption,
distribution, and excretion
for children 1 year and older are
more like adults than neonates.
00:32
But metabolism of drugs
is often faster in children 1 to
12 years of age than adults.
00:38
So make a special note of that.
00:41
3 of the 4 pharmacokinetic processes:
absorption, distribution, and excretion,
are more like adults than neonates.
00:50
But the metabolism of drugs
is often faster in children 1 to
12 years of age than adults are.
00:56
So that's a really key
and important point.
01:00
Okay. So let's look at,
sadly, some things that
happened to pediatrics,
their unique pediatric
adverse drug reactions.
01:08
There's a reason we do not
give aspirin to pediatric patients.
01:11
So aspirin and salicylates
can cause something
called Reye's syndrome,
which can be fatal.
01:17
So we just don't give aspirin
to children anymore.
01:21
People that are old
enough -- remember,
we used to call them baby aspirin
and they were kind of orange flavored
and little kids would chew them,
but they found that following a virus,
if you give a child
aspirin or a salicylate,
it can cause a fatal Reye's syndrome.
01:35
Now glucocorticoids, those
are corticosteroids.
01:39
We use them to suppress inflammation,
but we try not to use them with
pediatric patients because
it will suppress their growth.
01:46
So, while we do use glucocorticoids,
we try to use the smallest dose
for the shortest period of time,
and the least invasive route
that we can, if possible,
because we want to avoid
growth suppression.
01:58
Now, antibiotics like
chloramphenicol can
cause Gray syndrome and that
happens in neonates and infants.
02:05
That's a horrible syndrome.
02:07
They're vomiting,
they turn this horrible gray color,
their blood pressure drops,
their breathing gets really irregular,
and they cannot maintain
their temperature.
02:16
So that is called Gray syndrome,
and it happens with chloramphenicol,
that's an antibiotic.
02:21
Tetracycline, we don't
give to pediatric patients
because when you
think about tetracyclines,
think about teeth,
because it turns them brown.
02:31
People of a certain age
that were given tetracycline,
we just literally started
calling it tetracycline teeth
because they came
really brown and stained.
02:39
And most people have
had their teeth replaced
with veneers that experienced
tetracycline as a child.
02:44
Tetracycline binds to the calcium
and that's why it really gives
you problems in your teeth.
02:50
And finally, here's a weird one.
02:52
That we're talking about antibiotics,
we got chloramphenicol, tetracyclines,
and the last group is fluoroquinolones.
02:58
Which we give a ton of fluoroquinolones,
by prescription, but in children,
it has a rare tendency
to cause a tendon rupture.
03:07
So we try to avoid giving the group of
fluoroquinolones to children
because of the risk for tendon rupture.
03:13
Okay. So we've looked at
three groups of medications:
aspirin, glucocorticoids,
and antibiotics.
03:21
Aspirin is Reye's syndrome;
glucocorticoids, growth suppression.
03:26
Then we've got chloramphenicol
with Gray syndrome,
tetracycline's with your teeth,
and fluoroquinolones have
a possibility of tendon rupture.
03:36
So, how do you keep
these little guys safe?
What do we do as nurses to safely
give meds to the younger child?
Well, another thing you
want to keep in mind
is they're at risk for choking hazards.
03:48
So you don't ever want to force a crying
child to swallow a pill.
03:52
You know, even if it's a liquid,
you risk them aspirating it,
but if it's a pill,
that pill could actually get
lodged in their airway.
04:00
That's one of the saddest
codes we ever had
was a well-intentioned parent
had forced a child
to take a pill that they had
normally taken every day,
and ended up blocking their airway,
and that was one of the scariest
codes I have ever been in.
04:15
Now, you want to use
a child's preferred flavors.
04:17
On a happier note,
if there's a liquid
elixir that you're giving,
all the pharmacies have
different flavors that
you can put in that liquid to
help it be more palatable to the child.
04:27
And finally, one really fun idea
is you might put a really good taste
in their mouth that they like,
like a popsicle, before you have to give
them an oral medication.
04:36
If it's a flavor they
like and it's cold,
it'll decrease their sensitivity to
a really nasty taste of a medication.
04:44
Now, all kids love stickers
and they like positive words.
04:48
So when you can get
a child to take a medication,
make it a celebration,
make it a happy thing,
make it a good thing
for them by giving them
some type of reward.
04:57
Try to identify 1 parent or caregiver
in the home as the main
medication dispenser.
05:04
One of the risks of overdosing children
is if both well-intentioned
guardians or parents
are giving the child
the same medication.
05:12
So an option might be to
write down all medications in 1 place.
05:17
That way, if a parent
or a guardian is gone,
everyone is very clear on
how much medication
has been given to that child.
05:24
Okay. So we discuss tips for
safety with drug administration
for the younger child.
05:29
Now let's look at the older child.
05:31
Yeah, stickers don't work
with this age group anymore,
but the idea of the older
child is they're very aware
what other people,
their peers, and other
kids think of them.
05:40
So your job, if you want
drug administration to be safe,
is you want to simplify the regimen
and minimize the child's perception of
being too different from other people.
05:50
Remember what Junior High was like?
Yeah, you already feel
weird and awkward.
05:55
So having to go and take
a medication during school,
or having to go to the nurse can make
things real difficult for that student,
and they're less likely to be compliant.
06:04
So try and streamline and simplify
the regimen as most as you can,
so that student or that child
doesn't feel like they stand
out too much from their peers.
06:12
Help the older child
understand the purpose
of the medication and why
they really need to take it,
how they'll benefit from
taking that medication,
and give them as
much control as possible.
06:24
You want them to have choices
so that they can decide when,
where, and how, as much as you
can within the treatment plan,
they're going to take that medication.
06:33
Make sure that you identify 1 parent,
just like we talked about
with a younger child,
you want 1 parent to be the appropriate
main medication dispenser.
06:42
You want to make sure that you're
meticulous about writing down,
every day, the dosages and the times
of medication that you're getting,
so everyone is communicating
and on the same page.
06:51
And if it's a chronic regimen,
help the older child
find a support group.
06:56
Help them find other
kids their age that are
struggling with the same
time types of concepts
and ideas in taking medications
and feeling different than others.
07:06
That's one way to help them really
buy into the importance of
their drug administration plan.
07:11
Okay. Now that we've
talked about all that,
it's your chance to pause,
reflect, and recall.
07:16
So can you name a nursing intervention
for safe drug administration
that's unique to a younger child,
and one that's unique to an older child?
Take the time and just write those
in your margin of your notes.
07:33
Well, that wraps up our presentation in
lifespan pharmacology
for the pediatric patient.
07:38
Thank you for watching our video today