Welcome to our video on pharmacodynamics.
Now, you might be asking yourself,
“Why in the world do I need to know
Well, it’s actually a really cool
part of pharmacology.
So, let’s walk through how this
is going to benefit you
as a practicing nurse to understand
these really important concepts.
Okay, so if you understand how
remember we’ve discussed pharmacokinetics,
that’s how the body moves the
drug all the way through.
Pharmacodynamics is how the
drug impacts the body,
so it’s really important that
nurses understand that
plus all the individual patient variations.
Okay, so when you understand
you can advocate effectively and that
is your main role at the bedside.
Our job is to advocate for the patients:
to make sure they get the right medications,
they get them safely,
and they’re effectively doing what the
healthcare provider wants them to do.
It helps you make safe decisions
about your medication.
If I’m taking a medication, I want to make
sure it’s the safest choice for me
and I want the same thing for my patients,
and I know that you will too.
Now, in order for me to
assess the medication,
I need to share all that information
with the patient
and what they need to know
to be safe at home too.
So, I’ll use it to help educate the patients
about their medications.
So, it’s all about me being
a safe practitioner
and helping the patient carry that same
safe practice into their home setting.
So, let’s start with some basic
Now, the first one is a tongue twister,
so I’m going to say it very slowly—
maximal efficacy—there, I did it.
Now, let’s talk about what it is.
It’s the biggest effect a drug
can have on the body.
That is much easier to say
and to understand.
So, we’re looking for a big effect of a drug
that’ll have on the body. Remember,
is the effect of the drug on the body.
Now, potent drug, that’s easier to say,
but we’re talking if it’s a potent drug
that means that it produces an effect
at a relatively lower dosage.
Let me give you an example.
Morphine is a drug that
we use for pain control.
Most everybody is familiar
with what that name is,
also is used for pain control and
it’s a much more potent drug,
100 times more potent.
So, that’s what we mean when
we talk about a drug’s potency.
There may be 2 drugs that do similar things
but 1 is much stronger or potent.
The next term is receptor binding.
We’ll talk more about receptors as
we move through this presentation,
but we just want to introduce
you to the concept
that receptors are special proteins
that other substance bind to.
Now the last term on this slide is affinity,
and that’s just the strength
of the attraction.
Once the molecules are bound together,
how strong is that bond?
Okay, so those are just 4 basic terms
that you should understand in the
beginning of pharmacodynamics.