00:01 So, in a nutshell, let's wrap up the Beta-lactam antibiotics. 00:07 Beta-lactam antibiotics have a beta-lactam ring. 00:10 That's why we call it that because the beta- lactam ring in their chemical structure is included in penicillin, cephalosporins, monobactams, and carbapenems; those 4 groups of antibiotics. 00:23 Penicillin's been around a long time. 00:25 It's not as long as sulfonamides, but it has been around since the 1940s. 00:30 Now, beta-lactamases are the energy, the arch enemy of penicillins, and can inactivate that drug. 00:38 So, when a beta-lactamase inactivates the penicillin, we won't be able to treat the infection. 00:44 That's why we use those winning combinations we talked about. 00:48 Combining penicillin with clavulanic acid, tazobactam, or sulbactam allows the penicillin to overcome the beta-lactamases. 00:55 Now, that's way cooler than you're probably recognizing at this point in your study, but that was a very, very cool discovery. 01:03 Now, how does that penicillin work? Remember the P, it penetrates the cell wall and it weakens the cell wall, which causes cell lysis and death. 01:13 Penicillin only hits the gram- positive infections. 01:16 Remember, it is resistant to gram-negative infections and the most common side effect to penicillins is GI distress. 01:23 But remember, the most serious possible adverse effect is full blown anaphylaxis, which puts your patient at risk for severe respiratory distress. 01:35 That wraps up our talk of Beta-lactam Antibiotics. 01:38 Thank you for watching this video.
The lecture Penicillin: In a Nutshell (Nursing) by Prof. Lawes is from the course Anti-Infective Drugs in Nursing.
What is the most serious possible adverse effect of penicillin?
5 Stars |
|
2 |
4 Stars |
|
0 |
3 Stars |
|
0 |
2 Stars |
|
0 |
1 Star |
|
0 |
I'm studying for step 1, but this professor is much more in-depth and relates the meds to possible questions. rather than just reading from a slide.
1 customer review without text
1 user review without text