Osteogenesis (Bone Formation): Intramembranous Ossification (Nursing)

by Jasmine Clark

My Notes
  • Required.
Save Cancel
    Learning Material 2
    • PDF
      Slides Nursing Physiology The Skeletal System Bone Tissue.pdf
    • PDF
      Download Lecture Overview
    Report mistake

    00:01 So now let's talk about bone formation.

    00:04 The process of bone formation is referred to as ossification or osteogenesis.

    00:11 There are four situations where bone formation will occur.

    00:17 First, during embryological or fetal development.

    00:21 Second, when you are growing or as your bones grow before adulthood.

    00:28 Third, all throughout your life as your bones remodel.

    00:33 And finally, in a situation where you have to heal a fracture.

    00:41 So there are two forms of bone formation or ossification.

    00:46 There is intramembranous ossification and then there is endochodral ossification.

    00:52 Intramembranous ossification is usually associated with the formation of the flat bones like those in the skull.

    01:00 Whereas, endochondral ossification is usually associated within formation of the other bones in the body, and specifically the long bones in the body.

    01:11 So when it comes to intramembranous ossification or the formation of flat bones, there are four major steps.

    01:21 In the first step, the mesenchymal cells, in the mesenchyme of the fetus, are going to create an ossification center.

    01:31 These cells will then differentiate into osteoblasts cells.

    01:37 These osteoblasts cells then secrete extracellular matrix including collagen fibers.

    01:46 In the second step, as the osteoblasts are surrounded by the extracellular matrix that they secrete, they been differentiate into mature osteocyte cells.

    01:59 These osteocytes are now housed inside of little areas called lacunae.

    02:05 From their bone matrix begins to calcify.

    02:12 The third step is now the formation of the outer portion of the bone or the periphery of the bone.

    02:19 First, the mesenchyme is going to form a periosteum and the mesenchymal cells are now going to be replace with osteoblasts cells.

    02:29 As well, in this step, we start to form the trabeculae which are the little projections that are found in spongy bone.

    02:38 Also, blood vessels start to infiltrate through the holes that are found throughout the trabeculae.

    02:47 And the final step of intramembranous ossification compact bone is starting to be formed toward the periphery of the bone.

    02:57 The periosteum starts to form the fibrous periosteum layer on the outside of the bone.

    03:03 And inside of the bone, the spongy bone begins to be filled with red marrow, as the red blood cells are starting to form marrow tissue.

    About the Lecture

    The lecture Osteogenesis (Bone Formation): Intramembranous Ossification (Nursing) by Jasmine Clark is from the course Musculoskeletal System – Physiology (Nursing).

    Included Quiz Questions

    1. Flat bones
    2. Long bones
    3. Cartilage
    4. Joints
    1. Development of ossification center, calcification, the formation of trabeculae, and development of the periosteum
    2. Formation of osteoblasts, calcification, development of blood vessels, and development of the periosteum
    3. Calcification, the formation of trabeculae, development of periosteum, and development of osteoblasts
    4. Development of the periosteum, development of osteoblasts, calcification, and the formation of the ossification center

    Author of lecture Osteogenesis (Bone Formation): Intramembranous Ossification (Nursing)

     Jasmine Clark

    Jasmine Clark

    Customer reviews

    5,0 of 5 stars
    5 Stars
    4 Stars
    3 Stars
    2 Stars
    1  Star
    Dr Jasmine Clark explains well in details this making contents easy to digest.
    By Sophie A. on 18. March 2021 for Osteogenesis (Bone Formation): Intramembranous Ossification (Nursing)

    Perfect explanations and contents are easy to understand. I easily understand her contents than my lecturer's and I am appreciative of her teaching. It