00:01
Hi, welcome to our
series on Diabetes.
00:03
Now in this one,
I'm going to help you understand
normal insulin and
glucose control.
00:09
I want you to understand how it's
supposed to work in your body.
00:12
So be much clearer when you're
helping patients with diabetes.
00:15
So let's start at
the very beginning.
00:17
What is glucose?
Well, glucose is the main carbohydrate
that the body uses for energy.
00:24
It's always present in the blood ready
for the tissues to use when they need it.
00:29
So that's glucose,
main source of energy.
00:32
Now, glucose needs friend.
00:34
Glucose needs insulin.
00:37
Insulin is a hormone
that allows glucose to be absorbed
by the cells or the muscles.
00:42
So ready watch this.
00:44
We've got some pretty cool
special effects for you here.
00:48
So you see insulin just
bound to the receptor site
on the plasma
membrane of the cell.
00:53
Ready, let's watch it
again, I love this part.
00:55
So I've got insulin that's that
kind of golden colored shape.
00:59
It's heading toward
the receptor.
01:01
Boom, there you go.
01:03
Now, it's on the plasma
membrane of the cell.
01:06
Watch what happens next.
01:08
Okay, so see that?
That's opening and the cells can absorb
the extra glucose from the bloodstream.
01:14
That's how the glucose
makes it into the cell.
01:18
So the insulin hits
the receptor site
that opens the pathway for glucose to make
it from the bloodstream into the cell.
01:26
Remember,
patients that are insulin resistant
doesn't function that
way in their bodies.
01:32
But let's walk through the steps of
exactly what happens in your body.
01:36
What's the response that
food triggers in your body?
So let's say you're hungry.
01:42
Do you think your blood
glucose is high or low?
Well, when you're
hungry, it's likely low.
01:49
So, let's eat pizza.
01:51
I love pizza.
01:53
Now, what happens to your blood
glucose after you eat all these carbs?
Yes, I've seen you guys in class at
one o'clock trying to lecture to you
after you've eaten pizza.
02:03
And here's what it was on.
02:05
So you've had that pizza, right?
It was delicious.
02:08
What's going on in your body?
Well, we're going to
continue this discussion.
02:13
But I want to make sure you're
very clear what postprandial means.
02:17
So, if you wouldn't mind
go ahead and underline
postprandial in the notes there.
02:23
Perfect!
Because there's a very important
criteria you need to understand
and so do your patients.
02:29
Postprandial means after a meal.
02:32
But it's a very
specific window of time.
02:34
It is two hours after the first
bite, okay, or the start of the meal.
02:39
So not two hours after
the patient finishes,
but it's two hours after
the first bite of the meal.
02:47
Now,
if I was a non-diabetic client
their blood sugar will
likely be less than a 140.
02:53
For a diabetic client,
their blood sugar target is
for it to be less than 180.
02:58
But I'm just going to tell you it takes
a lot of effort for a diabetic client
who's having difficulty keeping
their blood sugar's maintained
to keep it less than
180 after eating a meal.
03:09
We'll get into more of that later,
but just have those numbers in mind.
03:13
Postprandial for non-diabetic, 2 hours
after the first bite, less than 140.
03:18
For a diabetic client,
we're shooting for less than 180.
03:23
So, let's break this
down step-by-step,
what happens when
your body eats food?
What response does food
trigger in your body?
So blood glucose levels rise
after that delicious rich
carbohydrate meal we call
pizza, right?
So in response to that glucose,
that blood sugar level getting higher
beta cells in the
pancreas are stimulated.
03:46
Now, they're stimulated to release
insulin into the bloodstream.
03:50
See the pancreas down there?
Yes, it's not a particularly attractive
organ, but it is very efficient.
03:56
It's endocrine function
involves hormones
and the hormone we're
talking about is insulin.
04:03
Eat the pizza,
blood sugar goes up,
body responds by the beta cells
in the pancreas releasing insulin.
04:10
Now remember what
insulin can do?
I know, there's our cool
special effects right there.
04:14
Because of insulin hitting
those receptor sites,
it opens up the pathway.
04:19
So the body cells can take up
the glucose from the bloodstream.
04:24
What's going to be the result?
Well, then the blood glucose levels
return to normal right around 90 to 100
and the stimulus for
insulin diminishes.
04:33
So blood sugar rises, beta cells
in the pancreas release insulin.
04:37
Insulin allows the body cells to take
up the glucose from the bloodstream.
04:41
Then the blood glucose
levels return back to normal.