So lets talk about those antacids.
they just neutralize stomach
acid in the moment, right?
They don't suppress stomach acid,
they just neutralize what's there.
So it coud mean magnesium hydroxide
which is milk of magnesia,
but that one also has some
issues - it can cause diarrhea.
And so if you pair it with aluminum
hydroxide, that can cause constipation
but it actually helps us kinda
balance things out.
Now what I want you to watch for is
magnesium toxicity in your patients.
If I have particularly an elderly patient or someone
whose kidneys are not functioning well and
sometimes it comes in the same patient I have an
elderly patient whose kidneys aren't functioning well
you want to watch them for signs
of magnesium toxicity, what?
Okay, if you are taking magnesium hydroxide, that's
what you're gonna watch for is, magnesium toxicity.
Same thing if I'm taking an antacid
whose main component is calcium,
I'm gonna watch him for signs
of calcium toxicity.
So we'll list those for you in your notes,
the signs and symptoms of magnesium toxicity
but I want you to be aware when you're
on a basic over the counter medication
and I have an elderly patient, or someone
whose kidneys are not working well,
or an old person whose kidneys aren't
working well - that's a real danger zone,
I'm gonna watch them for toxicity or
whatever the component is of that antacid.
Now sucralfate, that one's a... that's
a band-aid for the boo-boo as we say,
because it's really sticky, it's this gel
that you take orally
and it will attach to that ulcer and make
up like a liquid bandage in your stomach.
So it protects that wound against
the pepsin and the gastric acid.
Now it's really almost a risk-free drug,
there's a small risk of constipation
but it's actually pretty good, there's
not really any serious problems with it.
Misoprostol is the other one that
protects the stomach lining.
It will act as replacement for the endogenous
prostaglandins that you have in your body.
Now endogenous just means that's something
that my body normally makes by itself.
And remember how important
because they help my body ensure that it has
enough mucus and enough bicarbonate in that mucus
to neutralize that gastric acid and
protect from the pepsin.
So misoprostol is contraindicated in anyone
who is pregnant.
In fact this is often used as a drug to
So I would never want to give this medication
to someone who is of childbearing years
who wanted to have children or
we thought might be pregnant.
This is an absolute not appropriate
drug for that.
Now this one can cause some diarrhea.
That is kinda cool,
no diarrhea is never cool.
but I'm just telling if you look at these two drugs and
we put them together for you to kinda keep in mind,
they work differently.
Sucralfate is gonna coat the sore.
Misoprostol is gonna kinda
replace those prostaglandins.
Anybody can take sucralfate.
No one who is pregnant or thinking about
being pregnant can take misoprostol.
Might have constipation with sucralfate but I'm
gonna possibly have diarrhea with misoprostol.
So that's kinda put those together
so you can play those off and remember those.
You might want to draw lines in
between or make yourself notes,
but that will help it stick in your mind
when you're studying