Neurotransmitters and Hormones (Nursing)

by Jacquelyn McMillian-Bohler

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    00:01 Now, let's look at all of the elements and all the neurotransmitters and hormones together.

    00:06 And let's review what each one does.

    00:10 GnRH. Gonadotrophin-releasing hormone is released from...

    00:15 exactly, the hypothalamus.

    00:17 And it's responsible for stimulating the anterior pituitary to release...

    00:22 FSH, Follicle stimulating hormone; and LH, Luteinizing hormone.

    00:28 Those two hormones are responsible for helping not only the ovum and the follicle mature, but the LH specifically is going to trigger ovulation.

    00:38 Inside the ovary, we have the production of estrogen that's going to be early on, and that estrogen is going to help make things fluffy.

    00:47 It's going to help prepare the endometrial lining.

    00:49 So that is its function.

    00:52 Then progesterone is going to come in with the production of the corpus luteum.

    00:56 And it's going to help to stabilize the endometrium.

    00:59 So that's its function.

    01:00 And then at the corpus luteum is not influenced by hCG from a conceptus, then the corpus luteum is going to degenerate.

    01:08 Our estrogen and progesterone levels are going to fall.

    01:11 And we're going to begin our production of GnRH from the hypothalamus all over again.

    01:17 So let's see if we have all of that down.

    01:20 What you have in front of you is sort of a mixed up order of the menstrual cycle.

    01:23 I want you to now take a few minutes and see if you can put each of these steps of the process of the menstrual cycle in the correct order.

    01:32 And then we'll go through each one and see if you got it right.

    01:40 Okay, let's see how you did.

    01:43 So step one, the Gonadotropin-releasing hormone or GnRH is going to be released from the hypothalamus.

    01:51 Step two, GnRH is actually going to stimulate the anterior pituitary to then release FSH, Follicle Stimulating Hormone.

    02:01 And step four, the FSH actually stimulates the graafian follicle.

    02:06 So remember, the follicle is there.

    02:08 And then in step five, estradiol or estrogen levels increase because that's what's being produced.

    02:15 After the estrogen levels increase, we find that the estrogen is doing two things.

    02:21 First, it's going to increase the thickening of the endometrium and also it's going to continue to elevate as the ova matures.

    02:28 Now, you could probably put six or seven in opposite order, and it would still be okay.

    02:34 Finally, the GnRH is actually going to trigger the release of the luteinizing hormone.

    02:39 And that happens as a result of the estrogen.

    02:42 And then we have a surge in LH and that surge in LH is actually going to trigger the eruption of the egg.

    02:50 So that happens 24 to 36 hours after that surge.

    02:55 Under the influence of the LH the follicle that's left over is actually going to become the corpus luteum.

    03:01 And progesterone is going to be released.

    03:04 And the role of progesterone is to stabilize the endometrium.

    03:08 On step 13, if we don't have fertilization, and we don't have a conceptus, then estrogen and progesterone levels are going to begin to decline.

    03:17 And that's going to be a signal to shed the lining of the endometrium and begin the process again.

    03:23 So, I have one more slide in the correct order.

    03:26 So you can use this to go back and make sure that you have all the details all put together.

    About the Lecture

    The lecture Neurotransmitters and Hormones (Nursing) by Jacquelyn McMillian-Bohler is from the course Menstrual Cycle (Nursing).

    Included Quiz Questions

    1. Estrogen levels surge and the uterine lining thickens
    2. The ovum is expelled, and the corpus luteum forms
    3. Progesterone is released and stabilizes the endometrium
    4. GnRH triggers the release of the luteinizing hormone
    1. Low to nonexistent levels of human chorionic gonadotropin (hCG) hormone
    2. High levels of human chorionic gonadotropin (hCG) hormone
    3. High levels of follicle-stimulating hormone (FSH)
    4. Low to nonexistent levels of GnRH

    Author of lecture Neurotransmitters and Hormones (Nursing)

     Jacquelyn McMillian-Bohler

    Jacquelyn McMillian-Bohler

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