00:01
moisten and clean the air. Well, here is a couple
of complicated diagrams but I want to just
to look at the left-hand diagram first and
again try and point out the nasal cavity.
00:14
The very lower part of that diagram on the
left you can see the tongue and above that
the hard palate and then you have that latter
whitish area that represents the nasal cavity.
00:26
And just above it you can see a yellow structure.
It happens to be the superior chonchoae.
00:32
I will talk about that in a moment and above
that is olfactory epithelium. So just orientate
yourself with this particular figure first
and then I can go ahead and describe some
of the features that we are going to looking at.
The nasal cavity itself has three components.
00:53
The nasal vestibule is the very entry into
the nasal cavity, the nostril. It is actually
the skin, but it is served by a mucous type
for protective environment coming from the
nasal cavity. The bulk of the nasal cavity
you see is really the respiratory region. That
consists of a mucosa. Remember mucosa is the
internal lining of tubes that are exterior
to the body. This mucosa is a very important
mucosa and I am going to describe it in more
detail in a moment. And then above that, that
I pointed out before on that area just above
the superior conchae is the olfactory region.
That has a very special epithelium that allows
us to smell. We will now look across on the
right-hand side diagram. This is a section
taken as if the person is facing you and the
section passes through the nasal cavity.
01:58
The one we looked on the left was a mid-sagittal
section taken through the head region.
02:04
Well on the right-hand side, it is important that
you have a look at that diagram pick out the
nasal septum, dividing the nasal cavity into its two halves
and then the nasal cavity itself. But also
notice there are three projections. There
are three elevations of the mucosa and they
are supported by bone within them. Those elevations
are called chonchae. They are very very important.
02:35
They have respiratory epithelium, but they
increase the surface area of the nasal cavity
so that when you breathe air in through the
nose, the air is exposed to a large surface
area, it slows down. It swirls around a bit and
that is ideal for the air to come in contact
with the respiratory epithelium to carry out
the warming, the moistening and the cleaning.
03:01
Those chonchae have very very large networks of
blood vessels and they are responsible for
warming the air as well. Notice also on the
far right-hand and left-hand sides of the
nasal cavity in this image, there are huge spaces
called sinuses. Those sinuses are actually
also lined by respiratory tract epithelium
and there are very small entries into these
sinuses from the nasal cavity. Those sinuses
drain down into the nasal cavity. They drain
all the secretions of the respiratory tract
epithelium in that component of nasal
cavity, secretes and produces. Now sometimes when
we have inflammation of the nasal cavity,
influenza a common cold, the mucosa swells
and it often blocks off that region for drainage.
03:55
And if there is bacteria present, then they
can colonize and we get the condition that
we often experience called sinusitis, another
inflammatory problems associated with just
common colds. Well let us move now to a section
through the nasal cavity. On the left-hand
side, again it is taken through the front
view of a person, a front view through the
nasal cavity. On the right-hand side similarly
the section just has been oriented just a
little a bit off center or right angles, but
again pick up the hard palate. It is bone
and you can also see the nasal septum and
on either side will be the respiratory
component of the nasal cavity. You can see
that labeled there and then the huge round
bulge you see projecting into the nasal cavity,
is one of these chonchae consisting of large
blood vessels we call swell bodies. And I've already
stated of the function of those chonchae.
05:00
On the right-hand diagram, right at the top
of the nasal cavity is the olfactory region.
05:06
I am going to describe that in more detail
in a moment and down the bottom is the more
respiratory region where it is dominated by
this respiratory tract epithelium. And then
again is the chonchae and again if you look
at it very closely you can see it has got within
it glands and also the swell bodies or blood
vessels that help to warm the air. Well let us
have a look at this in a bit more detail.
First of all, we are going to have a look
at an area just near the nasal septum and
we are going to look at the epithelium of
respiratory tract mucosa. Here it is labeled
here and this type of epithelium then covers
the entire nasal cavity, in fact it covers
all the epithelial surfaces right down to
almost the terminal bronchioles and then it
changes and we will have a look at that when
we get down to that level of the conduits.
Well the respiratory epithelium when you look at
it, is a pseudostratified epithelium, meaning the
cells appear to be all on top of one another,
but it is only because you actually see the
nuclei on top of one another. All those cells,
in fact, are actually touching the basement
membrane. So it is called a pseudostratified
epithelium for that reason. And on top of this
epithelium are cilia. These cilia are very
important because there are glands within the
lamina propria, that connective tissue just
underneath the epithelium, these glands secrete
a mucous and a serous type component onto
the surface. The mucous component is secreted
by goblet cells within the epithelium.
07:00
You can see it is a very pale staining cell in
the epithelium. The serous secreting glands
buried into the lamina propria secrete this
watery fluid and that watery proteinaceous
type fluid is very important because on that
watery fluid sits the mucous. And the cilia
beat within that serous watery component and
as they beat in one direction they move the
mucous along the epithelial surface and that
mucous is sticky and therefore this epithelium
can trap debris that we inhale and move that
debris along in that mucous raft to where
we can swallow it or cough it out etc and
get rid of it from the body. That is a very
important part of this respiratory epithelium and
the nasal glands underneath remember secreting
this serous watery component. There is also
lots of blood vessels. In the bottom image,
you see a huge blood vessel. That is one of
the swell bodies, probably within the chonchae
that again warms the air as it pass through
the nasal cavity. Let us now have a look at