Monoallelic Expression

by Georgina Cornwall, PhD

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      Slides 03 The Goldilocks Principle IntroductionToMedicalGenetics.pdf
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    About the Lecture

    The lecture Monoallelic Expression by Georgina Cornwall, PhD is from the course Introduction to Medical Genetics. It contains the following chapters:

    • Monoallelic Expression
    • Monoallelic Expression: X-Inactivation

    Included Quiz Questions

    1. One allele is not present in the genome.
    2. One allele is randomly chosen.
    3. One allele is imprinted to not get expressed.
    4. One allele is part of the inactivated X chromosome.
    5. One allele is epigenetically silenced.
    1. Genomic Imprinting follows Mendelian inheritance.
    2. Some conditions may have different manifestations based on whether the mutation is paternally imprinted or maternally imprinted.
    3. Imprints are re-established during gametogenesis.
    4. Imprints remain part of our whole life (developmental and adulthood).
    5. Genomic Imprinting is an example of epigenetic inheritance.
    1. Barr body
    2. Barr chromosome
    3. Bar chromosome
    4. Bar body
    5. Bar allele
    1. Allelic dominance
    2. Epigenetic modifications
    3. X-inactivation
    4. Genomic Imprinting
    5. Barr body formation

    Author of lecture Monoallelic Expression

     Georgina Cornwall, PhD

    Georgina Cornwall, PhD

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