Medial Pontine Syndrome and Lateral Pontine Syndrome

by Craig Canby, PhD

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    The medial region or area of the pons can be damaged due to vascular insult. If it’s the medial structures of the pons, this would be medial pontine syndrome. This is going to be due to a lesion of the basilar artery that travels over the pons and gives rise to numerous pontine vessels to help supply them. Structures that are damaged in the medial pontine syndrome, there will be three. The corticospinal tract, the descending pathway is damaged. The medial lemniscus pathway, ascending tract is damaged. You’ll have damage to abducens nerve fibers, so you have a cranial nerve involvement as well. So two pathways and one cranial nerve being involved. We can see a couple of this very readily. At this level section, here’s your medial lemniscus here in blue. Then here you have your corticospinal components here in red. The abducens fibers are not visible at this axial level. We would have to be distal or inferior to this level. If injury to each one of these structures, what would we see or what would you see? First, the corticospinal tract symptoms. This would result in contralateral hemiparesis of upper and lower extremities. The medial lemniscus system is conveying vibration, conscious proprioception, and fine touch. If this pathway is lesioned, then you’ll have a contralateral loss of those functions. With abducens fiber injury, you will essentially inhibit or cause paralysis of the lateral rectus, the muscle that moves the eyeball laterally or moves it so that it adducts. If you can’t do that any longer, the eye will move medially and that is medial strabismus. You can also have injury or lesion of the lateral structural components of the pons. This would result in lateral pontine syndrome. This is also due to vascular insult, so it's a...

    About the Lecture

    The lecture Medial Pontine Syndrome and Lateral Pontine Syndrome by Craig Canby, PhD is from the course Brain Stem. It contains the following chapters:

    • Medial Pontine Syndrome
    • Lateral Pontine Syndrome

    Included Quiz Questions

    1. VI
    2. III
    3. XII
    4. IX
    5. IV
    1. Anterior inferior cerebellar artery (AICA)
    2. Middle cerebral artery (MCA)
    3. Posterior inferior cerebellar artery (PICA)
    4. Posterior cerebral artery (PCA)
    5. Anterior spinal artery (ASA)
    1. Loss of sweat glands secretion
    2. Loss of gustation from anterior 2/3rd of the tongue
    3. Ipsilateral facial paralysis
    4. Loss of salivary glands secretion
    5. Loss of lacrimal glands secretion
    1. Drooping of the upper eyelid
    2. Diplopia
    3. Excessive sweating
    4. Mydriasis
    5. Loss of corneal reflex

    Author of lecture Medial Pontine Syndrome and Lateral Pontine Syndrome

     Craig Canby, PhD

    Craig Canby, PhD

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