00:02
Now, in many instances,
your patient is going to need
more than one fluid bolus.
00:07
And why is that?
So under normal conditions,
fluid is going to go
into the bloodstream
and it's going to stay there
anywhere from 20 minutes
to 1 to 2 hours,
That's kind of the
half life of the fluid.
00:26
After that fluid has been
in the blood vessels
for that period of time.
00:30
It is going to start leaking
out of the blood vessels
and into the space
in between the cells.
00:39
So, infants and premature infants
often even have a
lower plasma oncotic pressure
and higher permeability
of the capillary wall.
00:48
So what does that mean?
That the little gaps in the
walls of your blood vessels
are even a little bit wider for
infants and premature infants.
01:00
And so the fluid that's
in those blood vessels
is just able to leak out into the
tissues around the blood vessels.
01:07
And this can also
happen when you're sick,
the gaps in your blood vessels
widen out a little bit.
01:12
And again, that fluid
that's in your blood vessels
starts to leak out
into the tissues.
01:17
So when you get a fluid bolus,
the fluid stays in the blood vessels
for a period of time,
but eventually,
it's going to start leaking out
into the tissues surrounding
the blood vessels.
01:30
This increases the shift of water
from the intravascular space
to that interstitial space.
01:37
And really, states like
sepsis makes this much worse.
01:43
So when the fluid starts to shift
into that interstitial space,
that is what is known
as third spacing.
01:50
So you'll hear that term
third spacing quite often
when you are talking about
ill and sick patients.
01:59
So, third spacing,
when that fluid starts shifting
into that interstitial space,
it really starts to
cause a lot of edema.
02:08
What does that mean?
Hands and feet, dependent areas
start to really swell.
02:14
Genitals is also an area
where fluid has a
tendency to collect.
02:20
Lungs are an area where fluid
has a tendency to collect.
02:24
And if you are lying in a bed,
anything that is low
has a tendency to collect fluids.
02:31
So the back of your head,
sometimes the back of your body,
and definitely hands and feet
are all areas that might become
quite quite swollen.
02:41
And it's really good to
kind of warn parents and
caregivers that this might happen,
because it can be quite shocking
for them to see their child
as they start swelling
with these fluid boluses.
02:54
So most importantly,
if you are going to perform
an intervention
like giving a fluid bolus,
just remember to
assess your patient
assess them before, during,
and after that intervention.