00:00
So we spent this first part introducing
you to what cirrhosis is in the liver.
00:05
You know, the three main categories
of causes are excessive alcohol,
excessive weight which leads to
non-alcoholic fatty liver disease
and chronic hepatitis.
00:15
So any chronic liver disease can
essentially end up in cirrhosis,
but those are the three most likely
causes of the disease process.
00:24
Okay, we had that big list before us
and now we're kind of zeroing in on
what am I most likely to see in a patient
who has pretty significant cirrhosis.
00:33
So let's start at the top
and work our way down.
00:37
Now we have the word
there that says coma
think about what you
know about the liver.
00:43
Well when the liver
breaks down protein,
what could cause coma,
well the liver breaks down protein
that ends up with ammonia
as a waste product
which the liver
then turns into urea
so it can be excreted
from the body
if the liver is not functioning
because it's cirrhotic.
01:01
I'm going to have
elevated levels of ammonia
which can cause neurotoxicity,
seizures coma and even death.
01:10
Another type of neuro
event are the asterixis.
01:13
Now, look at that, that's a sign
It's kind of called a flapping reflex
where the patient put their arms
up and tries to lift their hands
their hands will do this.
01:22
That is a classic
sign of cirrhosis.
01:26
So as far as neuro,
we've talked about coma
and you want to make sure
you've written a note out
there about ammonia levels,
then you've got asterixis which
thoughts that flapping sign
you might put that
there to remind you.
01:37
Now, let's take about what the patient
would look like on the outside.
01:41
Let's look at their skin.
01:42
So you've got spider
angiomas on there.
01:45
These are little tiny
branch like blood vessels
that you can see on the skin,
another one of the classic
signs of cirrhosis.
01:53
You might see bruising,
that's because have
a bleeding tendency
because your liver is
responsible for helping make
clotting factors and
working with vitamin K.
02:03
If they have cirrhosis,
they're going to
bruise very easily
if they just bump into
something with their arm
that's going to leave a bruise
because they're kind of bleeders.
02:12
Okay, so we've done neuro,
we've done what their
skin would look like.
02:18
Now we know they're
probably going to have some
extra fluid around so they're
going to be edematous,
but also there's some
other outward signs.
02:27
Gynecomastia and
testicular atrophy.
02:31
Now, these are two things that
you're obviously going to see with
male patients as it
involves the testicles
but what this comes from is the liver
has a really important role in hormones,
and when you have cirrhosis,
you end up having higher
levels of estrogen
and that's why you'll have
the atrophy of the testicles
and gynecomastia, which is a
development of breast on a male body.
02:55
Okay,
so we've gone In head-to-toe,
what I'd recommend you do is
pause the video think through the patient
from head-to-toe just talked about
and see how many
you can remember
of the manifestations of
cirrhosis in your patient.