00:01
Now, let’s talk about amyloid angiopathy. This is a third
category or
cause of an intraparenchymal hemorrhage. And here we see the
typical imaging
presentation. This is a patient who has suffered multiple
lobar hemorrhages in the
brain over time. You can see the area of hemorrhage is out
in the lobes of the brain
which is very different from the location of the
hypertensive hemorrhages and some
hemorrhagic transformations of ischemic infarcts. On the
non-contrast head CT on the
left, we see multiple areas of hemorrhage. One new
hemorrhage in the anterior right
frontal lobe and a little bit of hemorrhage behind that that
looked more acute and then
an area of subacute, perhaps early or late subacute blood in
the right posterior frontal
lobe. On the next two sequences, we’re looking at
susceptibility way to damages,
which highlight area of hemorrhage and we see new hemorrhage
in the right frontal lobe,
a subacute hemorrhage in the posterior aspect of the
occipital regions, and on the
far right image, these small areas of micro hemorrhage which
are highly suspicious,
and in some cases diagnostic of a diagnosis of amyloid
angiography. So, the combination
of lobar hemorrhage and in multiple micro hemorrhages should
raise high suspicion for
this diagnosis in patients presenting with new
intraparenchymal or intracranial
hemorrhage. Now, let’s talk about vascular lesions. This is
our fourth category or cause
of an intraparenchymal hemorrhage, and here we’re looking at
a patient who has had a
previously intervened vascular malformation presenting with
new hemorrhage.
01:34
This is a patient who had a prior clipping and you can see
the artifact on the far left CT
from a clipping of a prior AVM who presented with new focal
neurologic deficits,
had CT of the head that showed this area of new blood,
hyperdensity in that same area of
AVM. The CT scan on the left and in the middle demonstrate
that area of hemorrhage
and the catheter angiogram that you see on the far right
shows this area of blush of blood
which is a connection between the arteries and veins and
arteriovenous malformation
which increases the risk of hemorrhage within the brain. And
then our last or fifth
category of causes of intraparenchymal hemorrhage are
neoplasms. So, we can see
bleeding from brain metastases, secondary brain tumors and
primary brain tumors,
typically those that are more malignant. This patient
presented with new focal neurologic
deficits and was found to have this right hemispheric
hemorrhage with left hemibody
symptoms. On the head CT to the left, you can see a small
focus of hemorrhage, a very
small hemorrhage but a large area of edema around that,
which raises suspicion that this
hemorrhage may be occurring from an underlying lesion and
that's what’s causing
the swelling and the hemorrhage. An MRI was subsequently
performed, and you can
see that in the middle and right side of the screen. In the
middle, we see the T2 lesion
showing an underlying lesion with a large area of
surrounding edema and mass effect
as well as some early midline shift. And then on the far
right, the susceptibility weighted
image shows an internal area of hemorrhage but a larger area
of deficit around that
which is highly suggestive of an underlying tumor.