00:01
Hi, I'm Professor Lawes and welcome
to this portion of our video series,
where we're going to talk about
hypertrophic cardiomyopathy.
00:09
Now, we're going to start
with a picture of a heart.
00:11
And then I'll give you a tip
on how to remember
what this word means.
So, let's start with the heart.
00:17
Now, this is what
a normal heart would look like.
00:20
You can see we've
cut around the sacs,
so you can see into the inside.
00:23
Now, by the magic of
virtual reality, well close to it,
we're going to
cut through the heart,
so we can look specifically
at the left side of the heart.
00:34
Remember, the right side
receives the blood from the body,
the left side,
it leaves the heart
and goes out
to the rest of the body.
00:42
So, if we're going to look
at the left side,
that's the one that's responsible
for the heavy lifting,
or the pumping out
to the whole side.
00:49
So you saw our scalpel,
just slide down there.
00:53
Now, we're going to show you that
same view and a cleaner drawing.
00:57
Here, you see just
the left side of the heart.
01:00
Now, this is a normal heart.
You can see of the aorta,
the left atrium, the left ventricle,
this is a pretty good representation
of what a normal heart
would look like.
01:10
Now, notice those black bars
in the left ventricle.
01:14
They're kind of giving you
an idea of how thick
the wall of the ventricle is.
01:19
Look, what happens in
hypertrophic cardiomyopathy.
01:25
Wow, that's a really
significant difference.
01:29
So, HCM is
hypertrophic cardiomyopathy.
01:33
I always like to break that down to
help you use this in other videos,
and while you're studying
for your exams,
you can recognize these words.
01:41
"Hyper-" means excessive.
"-Trophic" is growth.
01:45
"Cardio" means heart,
"Myo" means muscle,
and "-pathy" -- bad news.
01:53
So this is affecting a
cardiac muscle, in a bad way.
02:00
And because it's excessively
growing, thickened wall.
02:05
The reason this happens is because
the heart has been overloaded,
but the heart is meant to be
able to contract and release.
02:15
This is no longer going
to be an efficient heart,
or even maybe even an adequate heart
with a wall that is this thick.
02:24
Let's talk about some context or
the epidemiology of cardiomyopathy.
02:28
First of all, it's abbreviated CMP.
02:33
Now, that might be
a little confusing to you,
but that stands for cardiomyopathy.
02:37
There's a descriptor word
that goes in front of that.
02:40
What we're talking about here
is hypertrophic cardiomyopathy,
but there's also
dilated cardiomyopathy.
02:48
Now, dilated cardiomyopathy
is the most common cause.
02:52
This one hypertrophic
cardiomyopathy
is less common than
the dilated CMP.
02:58
It also affects men more than
women, just like in the dilated.
03:04
But here's some places
where it gets different.
03:06
This is most commonly
an inherited cardiomyopathy,
Unlike dilated,
hypertrophic cardiomyopathy
is most commonly caused
by an inherited condition.
03:18
The sad thing is,
this is a well known
tragic and traumatic cause
of sudden death in athletes.
03:27
That's why those physicals
that are done on athletes
before they're cleared to play
are critically important
that the heart zones
are listened to
in a very quiet environment
by a skilled clinicians.
03:39
So they can catch signs of this
and deal with it
before the athlete is at risk.
03:45
Here are some causes of
hypertrophic cardiomyopathy.
03:50
Hypertension, that's one
because you're increasing
that workload of the heart.
03:55
And sometimes,
you can end up with
these hypertrophic impacts
on the wall.
03:59
Next, is aortic stenosis.
04:01
Now, aortic stenosis means that
valve is going to be stiff,
which would clearly increase
the workload of the heart.
04:09
It's having to push harder
against that stiff valve.
04:12
Kind of the same effect
as hypertension,
but just in a
very specific location.
04:18
Now, lastly, there's also
a genetic component.
04:20
Now, that gets pretty complicated
and I would not memorize that
if I were you.
04:25
But we just wanted you
to think about
"Hey, here are some major causes
of hypertrophic cardiomyopathy."
High blood pressure, a really stiff
aortic valve, and genetic causes.