So let's sum up in a nutshell.
Remember, ACE inhibitors end in "pril."
ARBs end in "tan."
and increases volume. Remember
we have the -- and --
Renin and angiotensin equals angiotensin I.
Angiotensin I + ACE = angiotensin II,
which is a very, very potent vasoconstrictor
and it also stimulates the
release of aldosterone,
which causes my body to hang on to sodium
and therefore, water follows.
That's what gives me the volume expansion.
ACE inhibitors, angiotensin II
receptor blockers, ARBs,
direct renin inhibitors,
and selective aldosterone receptor
antagonists are medications
that directly interact with the RAAS.
Now, before we go on, what I'd
like you to do is pause,
and see if you can write out the
RAAS by yourself.
Next, what I'd like you to do is take
each one of the drugs, listen to that
summary statement, ACE Inhibitors.
At what point in the RAAS do they interact?
Angiotensin II receptor blockers,
where do you put them?
Direct renin inhibitors, where do
they fit on your diagram?
Selective aldosterone receptor
antagonist, where do they fit?
Knowing where each of these medications
interact with the RAAS,
we're sure that you have a
of the risks and the huge benefits
of these medications
used to treat elevated blood pressure.
Keeping adverse effects, we want
to look for the key ones of
each of these medications.
And finally, let's grip those key
adverse effects for this
family and category of medications together.
Remember, we've got A, C, E:
angioedema, cough, and elevated potassium.
Also, remember that the prils
are really at risk for first dosed
but any of the meds can, kind of,
still put a patient at risk for that.
And finally, lot of these medications
should not be used with pregnant women.
Thank you for watching our video
on medications to treat hypertension.