00:01
Hi! Welcome to our
video series on HIV.
00:04
Now I might sound a little upbeat
for such a serious disease,
but I can't help it.
00:10
I am so impressed with
how far we have come
when HIV first came out.
00:15
It was a death sentence.
00:18
We were so afraid,
we didn't know what to do.
00:20
We didn't know how a spread,
we didn't know how it worked.
00:22
And now we know relatively
much much more about this virus
and it's no longer
a death sentence
with treatment,
a patient can live a full life,
but first up let's
understand how HIV works.
00:38
So what is HIV itself?
I love this picture.
00:42
It's like the classic villain
picture in some space battle
pretty cool-looking there.
00:48
Now for just a minute.
00:49
We're going to talk
about what this virus is.
00:52
I understand how it can
radically change someone's life,
but you have to step
back and appreciate
what this virus can actually do.
01:01
Do because it attacks
the body's immune system
say that's our biggest problem.
01:05
If a patient is HIV,
that means they have the virus.
01:09
We know that the worst case
scenario for a patient is
that their immune system
is going to be attacked.
01:15
So that's our focus.
01:17
We want to keep that viral
load as low as possible.
01:20
The fewest numbers of
virus in that patients body
is what our goal is
because we know the potential
to really knock out
the immune system
what this virus does
we want to keep the
fewest number possible
or they low viral
load in your patients?
So let's take a look at
the HIV virus itself.
01:40
Now, I've given you a
graphic drawing here.
01:42
You see the HIV glycoproteins,
the HIV RNA, the capsid
these are kind of the basic
working parts of the virus
because we're back
to your immune system
once a patient is
infected with HIV
if they don't receive treatment
now that's really important.
02:00
Don't miss that point this is
hey before we had the
effective treatment
that we have now.
02:06
or if someone
doesn't have access
or finances or resources
to get treatment,
here's what's going to happen.
02:12
Their immune system is going
to get weaker and weaker
and eventually they're not
going to be able to fight off
even opportunistic infections.
02:21
Now, normally you and I
opportunistic infection comes
our immune system
takes care of it.
02:27
So a healthy immune system
usually isn't that bothered by
an opportunistic infection,
but it gets that name
because it's taking advantage
of someone who's weakened
their immune system.
02:39
So that's the goal.
02:40
You'll hear me come back to that
over and over and over again
because that's what HIV does
if the patient doesn't
receive treatment,
their immune system becomes
weaker and weaker and weaker.
02:51
So it can't even
fight off the simplest
of opportunistic infections.
02:55
So let's talk about the
difference between HIV and AIDS.
03:00
How do you know does it matter
if your patients diagnosed
with HIV or Aids?
Oh, absolutely it matters.
03:08
Okay so HIV is just the
presence of the HIV virus
the human immunodeficiency virus
in the person's bloodstream.
03:17
That's what HIV positive means.
03:20
AIDS is much more intense.
03:23
Now, I'm talking about acquired
immunodeficiency syndrome.
03:28
That means my immune system
used to be functioning well,
but I've enquired
acquired this deficiency.
03:35
So I brought it on by when
I became HIV infected.
03:39
Now this encompasses a set
of symptoms and illnesses
that have developed
because they have
advanced HIV infection.
03:47
I've got lots and lots
of copies of the virus
in their blood stream
and it's essentially
destroyed the immune system.
03:55
Now, we're going to talk to
you about how that happens,
but it's important that you
understand the difference between
HIV and AIDS.
04:02
My quality of life is going
to be vastly different.
04:04
If I'm just HIV versus AIDS.
04:07
AIDS is really a significantly
advanced case of HIV.
04:13
Now there's also some criteria
that we used to really
use the diagnosis of AIDS.
04:19
So you have a CD4 T-cell count.
04:21
That's really low now
in normal CD4 T-cell count
probably be a good idea
for you to write this in,
but a normal CD4 T-cell count
is about about 500 to 1500.
04:33
So when a patient's
CD4 T-cell count
drops below 200,
men that's a sign
the immune system
is just not going to
be able to respond
and the way we wanted to.
04:45
So AIDS
they've got a CD4 T-cell count
one of our white cells
that's less than 200
and they have an
opportunistic infection.
04:55
Now, we just touched on
opportunistic infections.
04:57
So, you know, this is something
that my body should
be able to fight off.