00:00
So what do you think it means
if a patient has a
high serum creatinine
and a low urine creatinine?
Okay. Now think that through.
00:09
We're comparing the venous sample
to the urine sample,
if the blood sample
has high creatinine
and the urine has
low creatinine.
00:20
What does that tell us?
Right! kidney function.
00:26
We know creatinine is happening
because where does it come from?
Well, it comes from my
muscles needing energy.
00:31
And so that's creatinine
is that waste products.
00:34
So it's floating around
in my bloodstream.
00:36
It delivers it.
00:37
Remember at the beginning
when we followed
the blood supply it delivers it
to the kidney to be filtered.
00:43
So if the kidneys filtered it
means it hits that glomerulus that
tangle of capillaries and those tubules
and it should tell the body,
Hey this needs to leave in urine.
00:53
So if it's high in my blood
goes down to my kidneys
and it doesn't make
it into the urine
the kidneys weren't able to
filter that from the blood
and put it into your urine.
01:04
We've likely got
a kidney problem.
01:06
Might be an acute problem
might be a chronic problem,
but we definitely have a problem
that needs to be followed up.