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Hemoglobin (Hgb) (Nursing)

by Rhonda Lawes

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      Slides CBC Red Blood Cells.pdf
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    00:01 So let's take a look at hemoglobin.

    00:03 Now you see that we often shorten that to be Hgb.

    00:07 Now, its job is to carry oxygen throughout the body.

    00:09 Doesn't it feel great that that's really familiar to you? It's 95% of the dry weight of a red blood cell, so this is the meat of the red blood cell.

    00:18 Remember the red blood cell is just that sack that carries the hemoglobin.

    00:23 Now, it's a quaternary structure. That means it has 4 globular proteins. There's 4 units that can carry oxygen in an adult patient; 2 alpha and 2 beta.

    00:33 Now you don't need to ever memorize it's 2 alpha, 2 beta, but just know that there are 4 globular proteins in an adult hemoglobin.

    00:41 So each group has a heme molecule, and it has an iron center that loves to bind with oxygen.

    00:48 So each red blood cell has a hemoglobin.

    00:51 It can carry 4 oxygen components with it.

    00:55 So let's talk about what happens when you have extra cells.

    00:59 You've got polycythemia vera, that's a bone marrow is going crazy.

    01:03 You could be in a high altitude.

    01:05 Remember that's an adaptation to altitude.

    01:08 Now we talked about that previously.

    01:10 See if you can stop the video for just a minute and jot some quick notes as to why high altitude would give you a higher hemoglobin.

    01:22 Okay, hopefully, you remembered that in a high altitude, there's less oxygen available.

    01:28 So if you're there long enough, the body will adapt by putting out extra red blood cells.

    01:33 Extra red blood cells means a higher hemoglobin.

    01:37 Same thing with congenital heart disease.

    01:39 We've looked at each one of these previously.

    01:42 Anything that causes an elevated red blood cell will also cause the hemoglobin to be elevated.

    01:49 Same thing with anemia.

    01:51 Anything that causes a lower red blood cell will cause a lower hemoglobin.

    01:56 So if you ever see a patient that has a low hemoglobin, you want look for some of these problems that we've discussed in the other slides.

    02:04 So, chronic renal failure, because they don't have erythropoietin, which stimulates red blood cells.

    02:10 Pernicious or aplastic anemia, damage to your bone marrow, leukemia/lymphoma, where you have acute or chronic blood loss, or you've got some nutritional deficiencies.

    02:20 So, looking at this, like you don't have multiple slides to remember.

    02:24 We're just walking you through the concept that anything that causes elevated red blood cells will cause elevated hemoglobin.

    02:33 Anything that causes decreased red blood cells will cause decreased hemoglobin.


    About the Lecture

    The lecture Hemoglobin (Hgb) (Nursing) by Rhonda Lawes is from the course Complete Blood Count (CBC) (Nursing).


    Included Quiz Questions

    1. Anything that causes an increase or decrease in red blood cells will do the same to hemoglobin.
    2. Anything that causes an increase or decrease in red blood cells will do the opposite to hemoglobin.
    3. The red blood cell levels and hemoglobin levels have no relationship.
    4. Anything that causes an increase or decrease in red blood cells will do the same to hemoglobin, but in much smaller amounts.
    1. There are four globular proteins.
    2. Each group has a heme molecule.
    3. Fe (iron) lies in the center of each globular protein.
    4. It can carry six oxygen components.
    5. The nucleus binds tightly to oxygen.

    Author of lecture Hemoglobin (Hgb) (Nursing)

     Rhonda Lawes

    Rhonda Lawes


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