Glucagonoma (Alpha Cell Tumor) – Enteroendocrine Tumors

by Carlo Raj, MD

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    00:01 Let’s move on.

    00:02 Third, an alpha Islet cell tumor, alpha.

    00:06 What was the beta one? An Insulinoma.

    00:09 Know that because you might be thinking about MEN 1 and you have diagnosed it, but then they want you to know about Insulinoma, but they don’t see the answer choice as being Insulinoma, you choose beta Islet cell tumor.

    00:21 Now, alpha is… alpha Islet cell tumor, Glucagonoma, is rather rare, may then cause secondary diabetes because what does glucagon do? Gluconeogenesis, anti-insulin effect, hyperglycemia, diabetes mellitus.

    00:35 Do not forget about the huge derm issue.

    00:38 So, you can have diabetes mellitus, you can have your derm issue.

    00:44 A dermal pathology here will be the necrolytic migratory erythema, rash of lower extremity and bilateral end erodes, a type of erythema that you want to know for sure with Glucagonoma.

    About the Lecture

    The lecture Glucagonoma (Alpha Cell Tumor) – Enteroendocrine Tumors by Carlo Raj, MD is from the course Pancreatic Disease and Diabetes.

    Included Quiz Questions

    1. Pancreatic α-cells
    2. PP cells
    3. Neural crest
    4. Pancreatic β-cells
    5. Gastrin producing cells
    1. Diffuse presentation
    2. Involves lower extremities
    3. Bilateral
    4. Erosion of skin
    5. Blistering of skin

    Author of lecture Glucagonoma (Alpha Cell Tumor) – Enteroendocrine Tumors

     Carlo Raj, MD

    Carlo Raj, MD

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