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Glomerular Filtration Rate (GFR) – Urine Formation (Nursing)

by Jasmine Clark, PhD

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    00:01 The glomerular filtration rate is the volume of filtrate form permanent by both kidneys.

    00:08 This is normally about a 120 to a 125 milliliters per minute.

    00:15 The glomerular filtration rate or GFR is directly proportional to the net filtration pressure where the primary pressure is going to be our glomerular hydrostatic pressure.

    00:28 Also, the GFR is proportional to the total surface area available for filtration.

    00:36 Here, the glomerular mesangial cells are going to control this surface area by contracting.

    00:44 Finally GFR is directly proportional to filtrate membrane permeability.

    00:50 Which is much more permeable than the other capillaries that we find throughout the body.

    00:58 A constant GFR is important as it allows for our kidneys to make a filtrate and maintain our extra cellular homeostasis.

    01:08 The goal of local intrinsic controls are renal autoregulation is to maintain this GFR in our kidneys.

    01:18 Our GFR also affects our systemic blood pressure.

    01:22 An increased GFR causes an increased urine output with lower blood pressures and vice versa.

    01:31 Also, we have extrinsic controls which are necessary to maintain our systemic blood pressure.

    01:38 Our nervous system and our endocrine system are going to be the main extrinsic controls of the kidney.


    About the Lecture

    The lecture Glomerular Filtration Rate (GFR) – Urine Formation (Nursing) by Jasmine Clark, PhD is from the course Urinary System – Physiology (Nursing).


    Included Quiz Questions

    1. Allows the kidneys to make filtrate and maintain extracellular homeostasis
    2. Allows the kidneys to maintain a sodium-potassium balance and maintain fluid levels
    3. Allows the renin-angiotensin-aldosterone mechanism to function continuously
    4. Allows the kidneys to maintain cortisol-epinephrine balance and maintain intracellular homeostasis

    Author of lecture Glomerular Filtration Rate (GFR) – Urine Formation (Nursing)

     Jasmine Clark, PhD

    Jasmine Clark, PhD


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