Okay, let's look at some common,
everyday household things
that can cause interactions,
like the food we eat every day.
Food and drug reactions can be all over the map.
You may end up with a delayed
result, a decreased result,
an increased result, or sometimes,
it won't affect it at all.
Now, I recommend for students when they're
studying for NCLEX and for Pharmacology,
you cannot memorize drugs that should be
taken with food, drugs not with food.
That's what those stickers are for, so don't
try and overload your brain with that.
I'll teach you some really key concepts to know
which food interactions are
most important for you to know
as we walk through the rest
of this pharmacology class.
So we'll talk more about Parkinson's
meds and Coumadin, warfarin,
those types of food and drug interactions.
But as an overall concept, I want you to
be aware that food can interact with drugs
and it may be all over the map
in how it impacts the drugs:
delayed, decreased, increased, and
sometimes it doesn't impact it at all.
But I want to give you just a few examples
to kind of get you warmed up to the concept.
Grapefruit juice is really problematic.
If you take grapefruit juice
with cholesterol meds,
you're going to end up with
a higher risk for toxicity.
The patient ends up getting a higher dose
of that than that was originally ordered.
But also, grapefruit juice can decrease
the amount of medication in some others.
So, grapefruit juice is a big player.
If there's going to be one food
I was going to keep in mind,
it's like don't take grapefruit juice
with anything, just as a rule,
but particularly, with
Now, if I'm taking Coumadin or warfarin…
Warfarin is the generic name.
Coumadin is the trade name.
The…actually, the antidote for an
overdose of warfarin is vitamin K.
So vitamin K exists in all the
things that are good for you,
particularly green, leafy vegetables.
So, if we have a patient who's taking warfarin
and they love to eat a big kale salad every
day, we're going to have a problem.
So you'll learn as we go
over those anticoagulants,
if they really want to have that kale salad,
they're going to have to eat the
same size kale salad every day,
at the same time, and we'll have to
adjust their dosage to meet that.
Usually, people become less committed
to that kale salad every day,
if they have to eat it every day.
Now, the next category is salt substitutes.
The problem with these is that
they're made of potassium.
So you want to watch people with
renal problems really closely.
If they already have elevated potassiums,
you don't want them taking a salt substitute.
Or if they're on a medication
that raises their potassium,
you don't want them to be taking salt substitute.
And we talked before in other videos,
what we'll keep bringing this one up
for you, MAOIs are a psych drug.
And if you eat them with
it can cause a hypertensive
crisis for your patient.
So, here are 4 that actually
are worth you memorizing.
These are 4 that you want
to reinforce in your notes,
that you want to remember these as
really common food and drug interactions
that are particularly dangerous
to your patients.