So now let's talk about what
happens when things go wrong.
So first, if you were to get a wound on the
surface area of the skin or the epidermal layer,
The wound is going to
heal using two major steps.
First the stratum basale
layer or that layer of stem cells
is going to start to rebuild and
work toward closing that cut
Secondly, these cells are then
going to divide and start to replace
the original area of the
epidermis that was missing.
This is referred to as the
thickening of the epidermis.
If you get a deeper wound and you actually
extend into the dermis or the subcutaneous layer,
there's a few more steps that are involved.
First, once you break through the dermis,
this is going to elicit an inflammatory response.
The inflammatory response is gonna
include the dilation of blood vessels in the area,
the recruitment of several
different types of immune cells
as well as the recruitment of platelets which
are then gonna come in and create blood clot.
After the blood clot is formed, then
the epithelial cells and the epidermis
are going to start to migrate
again towards each other
similar to what happens
in epidermal wound healing
After this happens, just like
an epidermal wound healing,
this area is now able to
re-thicken or grow.
Now remember what goes
up must come down
So after this process is over and we
begin to start to replace those cells,
we need to return back to normal.
The blood vessels are going to go
back or constrict to their normal size
and those immune cells are going
to be taken away from the area.