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Today we're going to talk about
an epidemiological framework
called the chain
of transmission.
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We use the chain of
transmission to understand
how diseases are spread
from person to person.
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Now there are six
links in this chain.
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And in order to prevent disease,
all we have to do
is break the connection
between two of those links.
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So let's take a look at each.
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We'll start first
with the agent.
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This is what causes
disease to occur.
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And remember,
there are five different types of agents:
biological, chemical, nutrient,
physical, and psychological.
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Next, we have the reservoir,
and this is the place
where the agent
can live and multiply.
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Examples include humans, rats,
squirrels, and a few other animals.
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Next,
we have the portal of exit.
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Now the agent has to have a way
to escape to get out of the reservoir.
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And that's what this
is the portal of exit.
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And now it's important for us to
identify the mode of transmission,
there are several
possibilities here.
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The agent could be spread
through direct contact,
such as kissing an
infected individual.
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Or the mode of transmission
could be indirect spread,
such as food or
waterborne illnesses,
or an agent can be
spread by vector only.
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And remember,
a vector is a nonhuman carrier of disease.
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Next,
we have the portal of entry.
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This is the way that the
agent gets into the host body.
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And then finally,
we have the host.
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This is the individual who is susceptible
to being infected by that agent.
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Now again,
there's six parts here.
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And as long as they all connect,
diseases can be spread.
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However, all you have to do
to stop the spread of infection
is to break the chain
in just one place.
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It's also important to take into
consideration the environment.
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The circle surrounding the chain
here represents the environment,
which can have a profound influence
at almost any point in the chain.
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So let's walk through application
of the chain of transmission
for the disease
process of malaria.
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We'll start first
with the agent.
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Now remember,
the agent is what causes harm.
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In this instance, the agent is
the parasite that causes malaria.
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Now, can you think of what
type of agent that would be?
If you said a biological agent,
you are right.
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Next we have the reservoir.
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So this is a person who's
already been infected with malaria,
they've come in
contact with that agent.
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Next,
we have the portal of exit.
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Now remember,
in order for disease to spread,
we need a way for the
agent to exit the reservoir.
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This is called
the portal of exit.
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In the case of malaria,
the only way for the agent to spread
is through a vector
specifically through a mosquito.
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So the mosquito bite on the
reservoir is the portal of exit.
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Next,
we have the mode of transmission.
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And as I just said,
we need a mosquito to transmit
the parasite from the
reservoir to another person.
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So this means the mode of
transmission is vector transmission.
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Next,
we have the portal of entry.
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So we need a way for that agent
to get into the susceptible host body.
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In the case of malaria,
the mosquito bite provides
the portal of exit and
the portal of entry.
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However,
the portal of entry is the mosquito bite
on the new susceptible person.
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And then finally, we have that person
here we have the susceptible host,
who if bitten by the vector
is at risk of getting malaria.
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Now let's think about
the environment.
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For malaria,
a vector is needed to transmit the disease.
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So we have to take into
consideration the environmental factors
that encourage vector
reproduction and growth.
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So as I said earlier, the way that we
stop infection is by breaking this chain.
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So let's think of some ways
that we can break this chain up.
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What's one way to stop
the spread of malaria?
If you want it to break the chain links
between the vector and the portal of entry,
what is one strategy
that you might use?
So essentially,
what I'm asking is,
how would you prevent the mosquito
from biting the susceptible host?
Well,
what about the use of mosquito nets?
This could prevent the mosquito
from creating a portal of entry
by biting the potential host.
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Or what about the environment?
You could take into
consideration environmental efforts
that would eliminate the vector.
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We know that mosquitoes
thrive in areas with standing water.
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So by eliminating
that standing water,
we can eliminate the
vector and break the chain.
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The chain of transmission
is an epidemiological model
that explains how
diseases are spread.
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And it gives us the information
that we need to develop interventions
that protect individuals
and entire communities.