00:01 Hi. 00:02 Welcome to our video on diabetic medications. 00:06 Let's get started with a question. 00:08 So, after we read the question, I'm going to want you to pause the video and write your answer before you look at the rest of the presentation. 00:15 Ready? Okay, which type of diabetic patient cannot receive most of the oral anti-diabetic medications, and why? The answer is type 1 diabetic patients. 00:36 They don't benefit from most of the anti-diabetic medications because the beta cells of their pancreas have been destroyed. 00:44 The mechanism of action of most of these oral anti-diabetic medications is to stimulate insulin release from the pancreas. 00:52 So, the damaged pancreas of a type 1 patient is not able to accommodate these oral medications. 00:59 Now, when we're addressing anti-diabetic medications, we're looking at drugs that are against diabetes, so they're going to help us lower blood sugar. 01:07 There's 2 major groups. 01:10 Oral drugs, which I love the graphic that they put here for you, and non-insulin injectable drugs. 01:17 These are drugs that we use to treat diabetes, but they can't be swallowed. 01:21 They have to be injected and they're not insulin. 01:24 Most of the drugs that we'll discuss fall into the oral category, but there's a couple that we'll talk about in the injectable category. 01:31 Now, there are 7 families of oral anti-diabetic medications that we're going to go over. 01:36 So these drugs are taken by mouth. 01:39 There's the biguanides, the second generation sulfonylureas, the meglitinides -- we call those the glinides, the thiazolidinediones -- we just call them glitazones, the alpha-glucosidase inhibitors, the DPP-4 inhibitors, and the dopamine agonist. 01:57 So, now here's a study tip. 02:00 Mark this slide in your notes in your presentation. 02:03 Because it has 7 of the major classes and categories of oral medications that we use for type 2 diabetics, I want you to use this as a reference. 02:11 Go back to this slide to quiz yourself. 02:14 That's the most effective way to check your learning. 02:16 Just randomly pick a number, put your finger on it, or have somebody in your family pick a number between 1 and 7, and then go down the lists of things that you know about each drug as they call it. 02:27 So, ask your roommate to pick a number. 02:30 If they pick number 3, then share what you know about the glinides, why we use them, and what some of the adverse effects are. 02:37 The more you quiz yourself over and over, that spaced repetition will help you recall and retain that information. 02:45 Now, there's one more group. 02:46 They're the sodium-glucose co-transporter 2s, which is why we call them the SGLT-2 inhibitors. 02:53 This is another group of oral anti-diabetic medications, but this is what's really cool about this. 02:59 We can use it with type 2 diabetics, but it also may be helpful for type 1. 03:05 This is news. 03:07 They're doing clinical studies now, but it's really a cool development for type 1 diabetics. 03:12 Now, it does not replace insulin, but it may help them be more effective with their insulin, so stayed tuned. 03:19 We'll see what the research shows, but this 1 group, sodium-glucose co-transporter 2s might have some really incredible clinical applications for type 1 diabetics. 03:30 And it is the only one of the oral medications that right now, looking promising to deal with type 1 diabetics.
The lecture Diabetic Medications (Nursing) by Prof. Lawes is from the course Endocrine Medications (Nursing). It contains the following chapters:
A client with diabetes type 1 asks why oral antidiabetic medications are not an option. What is the nurse's best response?
What are examples of oral antidiabetic medications?
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