Welcome to our video on corticosteroids.
We're going to talk about the adverse
effects of endocrine medications.
Now, hey, I know that sounds like kind of a downer,
but this video is going to really help
you not understand just medications,
we're also going to give you some
pointers on endocrine diseases.
Now, Cushing's disease is called Cushing's
disease because it was discovered by --
you go it, Harvey Cushing.
So it's pretty cool that he figured this out.
But the point of showing you this
information first is Cushing's disease
and Cushing syndrome have
the same effect on the body.
Now, if I have Cushing's disease, my adrenal
gland is just really putting out the steroids,
or I've got some issues going
up here a little higher
with either my hypothalamus
or my pituitary gland.
Long story short, something's
gone wrong in my body,
so my adrenal glands are
pumping out extra steroids.
Cushing syndrome looks the same
as far as the side effects,
but Cushing syndrome is
something we do to patients.
When we give them corticosteroid medications,
they have extra steroids in their body.
It's not their body doing it.
They have these high steroid levels because
we are giving them the medication.
So, whether it's Cushing's disease, which
you likely won't see much of in your career
because you'll see far more of Cushing syndrome
because we give corticosteroids
in the States for lots of things.
So here's where the benefit of you hanging with
this in this video really comes into play.
Cushing's is excess ACTH.
Now, you're learning about and
endocrine disease, Cushing's disease,
and a syndrome as an adverse effect
of medication at the same time.
I love it when I can get double bang
for my buck when I was studying.
So, keep in mind, the cause of Cushing's
disease is my body going rogue,
but the cause of Cushing syndrome --
hey, we do that to you as healthcare providers.
We give you medications that will mimic the
same experiences like Cushing's disease.
So, that's why we're talking about it as
Cushing's disease and Cushing syndrome.
You have excess ACTH.
Now, I want to take a quick minute and
just break down that word for you.
This may feel painfully slow for
some of you, but that's okay.
Just celebrate that you already
remember this from our other videos.
I want you to put a box around the
first 5 letters of that word.
So pout a box around A-D-R-E-N.
See, the name tells me a lot about
what's going on with this hormone.
A-D-R-N tells me the target of
this hormone is the adrenal gland.
Now, I want you to underline C-O-R-T.
That tells me even more specific
information about the target.
The target is the cortex, the adrenal cortex.
Now, we know TROPIC.
We slap that onto any hormone,
that means put it out.
So, adrenocorticotropic hormone,
hormone is just a messenger.
So this is a messenger when
the message is received,
its target is the adrenal cortex, and
we want it to put out hormones.
That's what ACTH does.
Then, the adrenal cortex will release cortisol
and aldosterone, remember that one.