00:01 Hi. 00:02 Welcome to our video on corticosteroids. 00:04 We're going to talk about the adverse effects of endocrine medications. 00:08 Now, hey, I know that sounds like kind of a downer, but this video is going to really help you not understand just medications, we're also going to give you some pointers on endocrine diseases. 00:20 Now, Cushing's disease is called Cushing's disease because it was discovered by -- you go it, Harvey Cushing. 00:28 So it's pretty cool that he figured this out. 00:30 But the point of showing you this information first is Cushing's disease and Cushing syndrome have the same effect on the body. 00:39 Now, if I have Cushing's disease, my adrenal gland is just really putting out the steroids, or I've got some issues going up here a little higher with either my hypothalamus or my pituitary gland. 00:49 Long story short, something's gone wrong in my body, so my adrenal glands are pumping out extra steroids. 00:58 Cushing syndrome looks the same as far as the side effects, but Cushing syndrome is something we do to patients. 01:05 When we give them corticosteroid medications, they have extra steroids in their body. 01:11 It's not their body doing it. 01:13 They have these high steroid levels because we are giving them the medication. 01:18 So, whether it's Cushing's disease, which you likely won't see much of in your career because you'll see far more of Cushing syndrome because we give corticosteroids in the States for lots of things. 01:33 Okay. 01:34 So here's where the benefit of you hanging with this in this video really comes into play. 01:39 Cushing's is excess ACTH. 01:42 Now, you're learning about and endocrine disease, Cushing's disease, and a syndrome as an adverse effect of medication at the same time. 01:52 I love it when I can get double bang for my buck when I was studying. 01:55 So, keep in mind, the cause of Cushing's disease is my body going rogue, but the cause of Cushing syndrome -- hey, we do that to you as healthcare providers. 02:06 We give you medications that will mimic the same experiences like Cushing's disease. 02:12 So, that's why we're talking about it as Cushing's disease and Cushing syndrome. 02:17 You have excess ACTH. 02:21 Now, I want to take a quick minute and just break down that word for you. 02:24 This may feel painfully slow for some of you, but that's okay. 02:28 Just celebrate that you already remember this from our other videos. 02:32 I want you to put a box around the first 5 letters of that word. 02:36 So put a box around A-D-R-E-N. 02:40 See, the name tells me a lot about what's going on with this hormone. 02:45 A-D-R-N tells me the target of this hormone is the adrenal gland. 02:50 Now, I want you to underline C-O-R-T. 02:54 That tells me even more specific information about the target. 02:58 The target is the cortex, the adrenal cortex. 03:02 Now, we know TROPIC. 03:03 We slap that onto any hormone, that means put it out. 03:07 So, adrenocorticotropic hormone, hormone is just a messenger. 03:14 So this is a messenger when the message is received, its target is the adrenal cortex, and we want it to put out hormones. 03:23 That's what ACTH does. 03:26 Then, the adrenal cortex will release cortisol and aldosterone, remember that one.
The lecture Cushing Disease and Cushing Syndrome (Nursing) by Prof. Lawes is from the course Endocrine Medications (Nursing). It contains the following chapters:
What is the cause of both Cushing's syndrome and Cushing's disease?
Which gland releases adrenocorticotropic hormone (ACTH)?
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