Now, there are 2 groups of NBPs. We've got 2 types. They are competitive or non-depolarizing
neuromuscular blockers and depolarizing neuromuscular blockers. That's just the way they
work a little bit more of their mechanism of action, but they have a different effect on your
patient. So, let's compare them. I always like to use a chart format because it helps me see
the information more clearly. So, as far as onset of paralysis, both competitive and depolarizing
are rapid. They both happen quickly. Now, the peak for the competitive or the non-depolarizing
takes about 20 to 45 minutes for that to really hit, and then it will decline after that. For the
depolarizing, it peaks at a minute, and it fades after 4 to 10. So, with the depolarizing, they
don't last as long. They kick in quicker for their peak effect, but they also wear off faster.
Now, with the competitive, recovery will be complete in 1 hour, and with the depolarizing,
it's ultra short-acting. So look, the peak is gone after 4 to 10 minutes. It's going to wear
off much quicker. So, that's why we use competitive or non-depolarizing neuromuscular
blockers for longer procedures, not the depolarizing ones. Okay, now that was a lot of
information. No worries. I would recommend that you pause the video, stop over and review
that again, make sure I would write in non-depolarizing above the column where it says
competitive and then I'd just spend some time laying that foundation of information down, so
that's clear before you move on. Then, restart the video again and join us. So, let's look at
some drug names of both the competitive neuromuscular blockers and the depolarizing
neuromuscular blockers. I'll just let you know there's a lot more competitive ones than there
are depolarizing ones. So, for the competitive, you've got atracurium. Look what these end in.
Look at those last words. You've got i-u-m at the end of each one of these. So, that's one clue
to help you remember what these are. Now, the depolarizing example we have is succinylcholine.
You'll hear them call that succs a lot of times. So, I know it kind of sounds weird to say that
in a medical setting, but a lot of times people refer to succinylcholine as succs.