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Cholesterol and Statins: In a Nutshell (Nursing)

by Rhonda Lawes

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      Slides 06-08 Cholesterol-lowering Medications.pdf
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    00:01 Let's wrap up this look at statins.

    00:03 Cholesterol is not a bad thing.

    00:05 It is in every membrane of our cells.

    00:08 We think LDL is the biggest contributor to atherosclerosis.

    00:12 So, lifestyle, diet, and exercise can help significantly impact lowering our LDL levels and raising our HDL levels.

    00:22 Statins are the most effective drug for lowering blood LDL and cholesterol levels if diet and lifestyle weren't enough.

    00:29 Now, statins increase the number of LDL receptors in the liver, remember? That's a good thing because if I have more receptors in the liver, I get more LDL into the liver and out of the bloodstream.

    00:41 The target we're looking for is an LDL < 100, or if you have high risk, < 70.

    00:48 Most of the statins should be given at night for the most effective treatment for lowering LDL.

    00:54 And remember, there are 2 rare adverse effects.

    00:57 One is hepatotoxicity – remember, damage to your liver -- and myopathy.

    01:02 Now, you'll see a new word there, rhabdomyolysis.

    01:06 That is just a form of severe muscle damage. It's so bad that it ends up throwing your patient into renal failure.

    01:14 So myopathy is muscle damage.

    01:16 Rhabdomyolysis is such a severe muscle damage that it ends up causing renal failure.

    01:22 So, you want to monitor both the liver function tests and creatinine kinase levels.

    01:28 Thank you for watching our video today.


    About the Lecture

    The lecture Cholesterol and Statins: In a Nutshell (Nursing) by Rhonda Lawes is from the course Cardiovascular Medications (Nursing).


    Included Quiz Questions

    1. Statins increase the number of LDL receptors in the liver.
    2. Most statins should be given at night for effectiveness in lowering LDL.
    3. Statins may have rare adverse effects such as hepatoxicity and myopathy (rhabdomyolysis).
    4. Statins decrease the number of LDL receptors in the liver.
    5. Most statins should be given in the daytime for effectiveness in lowering LDL.

    Author of lecture Cholesterol and Statins: In a Nutshell (Nursing)

     Rhonda Lawes

    Rhonda Lawes


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