00:01 Let's wrap up this look at statins. 00:03 Cholesterol is not a bad thing. 00:05 It is in every membrane of our cells. 00:08 We think LDL is the biggest contributor to atherosclerosis. 00:12 So, lifestyle, diet, and exercise can help significantly impact lowering our LDL levels and raising our HDL levels. 00:22 Statins are the most effective drug for lowering blood LDL and cholesterol levels if diet and lifestyle weren't enough. 00:29 Now, statins increase the number of LDL receptors in the liver, remember? That's a good thing because if I have more receptors in the liver, I get more LDL into the liver and out of the bloodstream. 00:41 The target we're looking for is an LDL < 100, or if you have high risk, < 70. 00:48 Most of the statins should be given at night for the most effective treatment for lowering LDL. 00:54 And remember, there are 2 rare adverse effects. 00:57 One is hepatotoxicity – remember, damage to your liver -- and myopathy. 01:02 Now, you'll see a new word there, rhabdomyolysis. 01:06 That is just a form of severe muscle damage. It's so bad that it ends up throwing your patient into renal failure. 01:14 So myopathy is muscle damage. 01:16 Rhabdomyolysis is such a severe muscle damage that it ends up causing renal failure. 01:22 So, you want to monitor both the liver function tests and creatinine kinase levels. 01:28 Thank you for watching our video today.
The lecture Cholesterol and Statins: In a Nutshell (Nursing) by Rhonda Lawes, PhD, RN is from the course Cardiovascular Medications (Nursing).
What information should a nurse consider when a client is taking statins? Select all that apply.
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