Let's wrap up this look at statins.
Cholesterol is not a bad thing.
It is in every membrane of our cells.
We think LDL is the biggest contributor
diet, and exercise can help
lowering our LDL levels and
raising our HDL levels.
Statins are the most effective
drug for lowering blood
LDL and cholesterol levels if diet
and lifestyle weren't enough.
Now, statins increase the number of LDL
receptors in the liver, remember?
That's a good thing
because if I have more
receptors in the liver,
I get more LDL into the liver and
out of the bloodstream.
The target we're looking for is an LDL < 100,
or if you have high risk, < 70.
Most of the statins should
be given at night
for the most effective treatment
for lowering LDL.
And remember, there are 2
rare adverse effects.
One is hepatotoxicity –
remember, damage to your liver -- and myopathy.
Now, you'll see a new word
That is just a form of severe muscle
damage. It's so bad
that it ends up throwing your
patient into renal failure.
So myopathy is muscle damage.
Rhabdomyolysis is such a severe
muscle damage that it ends up
causing renal failure.
So, you want to monitor both
the liver function tests
and creatinine kinase levels.
Thank you for watching our video today.