00:00 Well that's what we talked about. 00:02 This is an actual case. 00:04 A female patient presents to the ER with severe signs of muscarinic poisoning. 00:10 Okay, so exhausted, irritiable, muscular cramps, salivation, frothing from the mouth, sweating, lacrimation, blurring of vision, miosis, ptosis, bronchorrhea, cough, wheeze, tachypnea rhonchi, bradycardia, hypotension, abdominal cramps, vomiting, diarrhea. 00:25 That is the definition of a bad day. 00:29 See the good thing is if you're in ER and you already know how muscarinic receptors work, we know that she had mushrooms, we know you have muscarinic poisoning. 00:38 Or in other words, you've got too much muscarinic agonists. 00:43 and we know how to treat that, right? You would give a muscarinic antagonist like atropine to fix all of those problems because see she had all those problems, let's not go through them again - that's a very long list. 00:59 I can't imagine feeling like that, right? But if we give you a muscarinic antagonist like atropine, look what's gonna happen - We're gonna dilate the pupils, well that's not such a big deal but we're gonna decrease all of that frothing at the mouth, we're gonna raise that heart rate, we're just gonna raise that low blood pressure, we're gonna open those airways so you can breathe better and hopefully you're not wheezing like that and we're gonna settle that gut down. 01:29 This is what somebody who has mushroom poisoning or muscarinic agonist poisoning needs as a fix. 01:36 They need a muscarinic antagonist. 01:39 So if you wanna know how to survive mushroom poisoning, atropine or a muscarinic antagonist is your best bet.
The lecture Case Study: Female with Mushroom Poisoning (Nursing) by Rhonda Lawes, PhD, RN is from the course Peripheral Nervous System (PNS) Medications (Nursing).
What are signs and symptoms of severe muscarinic overdose?
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