00:00
Well that's what we talked about.
00:02
This is an actual case.
00:04
A female patient presents to the ER with
severe signs of muscarinic poisoning.
00:10
Okay, so exhausted, irritiable, muscular cramps,
salivation, frothing from the mouth, sweating,
lacrimation, blurring of vision, miosis,
ptosis, bronchorrhea, cough, wheeze, tachypnea
rhonchi, bradycardia, hypotension,
abdominal cramps, vomiting, diarrhea.
00:25
That is the definition of a bad day.
00:29
See the good thing is if you're in ER and you
already know how muscarinic receptors work,
we know that she had mushrooms, we
know you have muscarinic poisoning.
00:38
Or in other words, you've got
too much muscarinic agonists.
00:43
and we know how to treat that, right?
You would give a muscarinic
antagonist like atropine
to fix all of those problems because
see she had all those problems,
let's not go through them
again - that's a very long list.
00:59
I can't imagine feeling like that, right?
But if we give you a muscarinic antagonist
like atropine, look what's gonna happen -
We're gonna dilate the pupils,
well that's not such a big deal
but we're gonna decrease all
of that frothing at the mouth,
we're gonna raise that heart rate, we're
just gonna raise that low blood pressure,
we're gonna open those airways so you can breathe
better and hopefully you're not wheezing like that
and we're gonna settle that gut down.
01:29
This is what somebody who has mushroom poisoning
or muscarinic agonist poisoning needs as a fix.
01:36
They need a muscarinic antagonist.
01:39
So if you wanna know how to
survive mushroom poisoning,
atropine or a muscarinic
antagonist is your best bet.