00:00
Next, let's talk about myelopathy and the difference between a conus medullaris and
cauda equina syndrome. This is critically important for evaluating patients and for
addressing test questions and multiple choice questions in patients who may be
presenting with myelopathy. And let's start with a case. This is a 22-year-old who
presents with low back pain, saddle anesthesia, and bowel and bladder retention.
00:27
These findings are already pointing us to possible spinal cord pathology with the
prominent bowel/bladder dysfunction and saddle anesthesia. As we interrogate some
of these symptoms a little bit more, we find that the back pain radiates to the lower
extremities bilaterally with associated tingling and numbness. There are radiculopathy
symptoms going down the legs. The pain radiates bilaterally into her lower extremities.
00:51
In terms of the constipation and retention symptoms, they started 3 weeks ago and
is progressively worsening. On retrospect, the patient reports low back pain with
radiation into her legs bilaterally for approximately 1 year, so a longer history of back
pain. Prior to that, approximately 3 years ago she had mentioned once or twice this
similar radiation of pain down her legs. Examination of the left lower extremity shows
asymmetric weakness with dorsiflexion, 5/5 full strength with knee flexion and knee
extension, and the right leg is full strength 5/5 throughout. On sensory exam, sensation
is intact to touch and pain bilaterally in the upper extremities, decreased to light
touch over the perianal region and in the posterior thighs bilaterally. There is
asymmetric hypo and even areflexia in the legs bilaterally and rectal tone is absent.
01:42
These findings are clearly concerning for a spinal cord disorder and this asymmetric
presentation suggest that this may actually fall outside of the spinal cord and in that
region of the cauda equina where there is some problem picking off different nerves
that is descending to the legs and to the autonomic supply to bowel and bladder
function. And here we see some of the key features of this case. Decreased light
touch in the perianal region going along with that saddle anesthesia which is highly
concerning for a lower cord problem either conus medullaris or cauda equina syndrome.
02:17
We also see that this patient has asymmetric hyper and areflexia and rectal tone
is absent which also points us to a pathology in that area. So what's the most likely
diagnosis? Transverse myelitis, cervical spondylosis, lumbar radiculopathy, or a cauda
equina tumor. Well, transverse myelitis is unlikely to be the underlying etiology in this
case. A transverse myelitis is a central nervous system disorder. These patients
present with prominent upper motor neuron signs. There can be some asymmetry
but often the increase in reflexes or upper motor neuron signs are present bilaterally
which is not the case for this patient. This also doesn't sound like cervical spondylosis.
03:00
Cervical spondylosis is also a central nervous system disorder, a disorder affecting
the central nervous system nerves. Patients present with upper motor neuron signs,
symptoms beginning in the legs and then developing and progressing into the hands
with external compression which we don't see in this case. Lumbar radiculopathy
doesn't sound like the right diagnosis for this patient either. The patient presents
with symptoms of diffuse lumbosacral dysfunction, not a single nerve that's involved
but multiple nerves throughout the lumbosacral plexus which is inconsistent with
what we'd expect for a lumbar radiculopathy. And ultimately, this syndrome was
consistent with cauda equina syndrome and this patient was diagnosed with a cauda
equina tumor. Patients present with cauda equina syndrome and have diffuse lower
motor neuron symptoms of the spinal nerve roots which you are seeing in both the
strength, sensory, and reflex exam for this patient. And here we have the MRI for
this patient. We're looking at a lumbar MRI. These are the T1 post contrast images
and we see a large homogenously enhancing mass in the lumbar spine on the sagittal
and also on the axial. On the axial, it's taking up nearly the entirety of the thecal sac.
04:14
This was compressing slowly progressing those cauda equina nerve roots resulting
in cauda equina syndrome and required surgical intervention. And this is one example
of the types of pathology that we can see in the cauda equina.