Brain Abscess: Diagnosis

by John Fisher, MD

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    00:01 So, obviously, imaging of the brain is needed and what we’re looking for is computed tomography, which will show you a hypodense center with surrounding ring enhancement.

    00:15 And the MRI is actually more sensitive than the CT scan, especially for toxoplasmosis.

    00:22 And if we have some spinal fluid, and sometimes it's not safe to get spinal fluid because of increased intracranial pressure, we would do PCR, looking for various causes.

    00:35 Now, if we can safely aspirate the abscess, we will do so.

    00:40 And if the Gram stain shows you mixed flora, we would design therapy according.

    00:46 So, we would expect aerobic and anaerobic cultures to be done.

    00:51 We would expect an acid-fast stain to be done.

    00:54 We would do fungal stains.

    00:56 In other words, a patient shouldn't have to undergo an invasive procedure without essentially getting everything known to man done on the specimen.

    01:08 If they have a suspicion of Toxo, we can do the serology and a CSF PCR.

    About the Lecture

    The lecture Brain Abscess: Diagnosis by John Fisher, MD is from the course CNS Infection—Infectious Diseases.

    Included Quiz Questions

    1. Hypodense center with surrounding ring enhancement.
    2. Hyperdense center with surrounding ring enhancement.
    3. Hypodense center with indiscreet boarders.
    4. Hyperdense center with indiscreete boarders.
    5. Diffuse edema without evidence of localized lesion.
    1. PCR
    2. Gram staining
    3. Aerobic and anaerobic culture
    4. Acid fast staining
    5. Fungal staining

    Author of lecture Brain Abscess: Diagnosis

     John Fisher, MD

    John Fisher, MD

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