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Biological Bases of Nervous System Disorders – Psychological Disorders (PSY)

by Tarry Ahuja, MD
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    Okay. So now what we’re going to do is we’re going to start going a little bit deeper into each specific state that I talked about. We’ll start with schizophrenia. And so we know that schizophrenia has a very strong genetic link and you can be genetically predisposed to this disorder. So the way we always figure this out is through twin studies and we looked at both monozygotic and dizygotic twins. And in twin studies, we know that if one twin has it, it’s a 50% chance that the other will have it or some type of form of schizophrenia. We know that genetics provides a biological predisposition and environmental stressors can elicit the onset. So, in English, if it runs in your family, so if your father or your mother or your grandfather or grandparents have it, it's passed on through genes and you might be what I like to say is prewired for it. It doesn’t necessarily mean you’re going to get it, but you’re prewired or you have the predisposition to potentially get it. And if the appropriate environmental stressors or triggers are there, you can initiate the disease or the onset of the disease. So there are a lot of debates sort of in the community around what causes it and I don’t think anybody agrees on the exact cause, but we do agree that there’s a strong genetic link, you would be predisposed and there are things in the environment around you that might trigger or activate that expression of the disease. Now, there’s a dopamine hypothesis of the disease and when you see terms like this, what they’re trying to do is understand and express the underlying mechanism behind why they think this disease is being expressed. This theory is still obviously up...

    About the Lecture

    The lecture Biological Bases of Nervous System Disorders – Psychological Disorders (PSY) by Tarry Ahuja, MD is from the course Individual Influences on Behavior. It contains the following chapters:

    • Schizophrenia (PSY, BIO)
    • Depression (PSY, BIO)
    • Alzheimer's Disease (PSY, BIO)
    • Parkinson's Disease (PSY, BIO)

    Author of lecture Biological Bases of Nervous System Disorders – Psychological Disorders (PSY)

     Tarry Ahuja, MD

    Tarry Ahuja, MD


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