00:00
Now I want to talk about
ART, antiretroviral therapy
and CD4 T-cells.
00:06
These patients will
have regular blood tests
because we want to
measure the levels
of virus in their body.
00:10
That's the viral load
and we also want to look at the
strength of their immune system.
00:15
So we'll look at
the CD4 T-cell count
that's going to tell us how
well the treatment is working.
00:22
So, how do we evaluate
treatment for HIV?
We're going to look
at what two things.
00:28
Good! The viral loads these
are both going to require
the test of viral load
and a CD4 T cell count
which can be done
on your basic CBC.
00:39
If we've got a differential
so if the CD4 T-cell
count is too low.
00:44
Remember the bottom
number for normal is 500.
00:47
If it's too low then we know
that hey something's going on.
00:51
Let's ask some more questions.
00:52
Let's do some more assessments.
00:54
Let's figure out is the
patient able to be compliant
with the medication.
00:58
With out judgment.
01:01
The minute you make
the patient feel guilty or bad
or why aren't you doing this?
They'll shut down and
stop talking to you.
01:08
That's not what we want,
it doesn't help anybody.
01:11
We want open communication.
01:12
So if you notice a lot
of work is changing
there might be an issue.
01:16
The patient is challenged
in staying compliant
with taking it every day.
01:20
So make sure you assess that
maybe the medications
aren't working,
but they may not be working
because it's a compliance issue.
01:27
See, that's our job as
Healthcare Providers
is to figure out why
to monitor to assess
and then to have adult
and open communication
with the client to
help them resolve it.
01:39
So when were assessing
the treatment
we look at the CD4 T-cell count.
01:42
So this will let us know how
strong the immune system is.
01:45
Why?
Right, because CD4 T cells.
01:50
These are like the
helper cells in my body.
01:52
They helped my immune
system be all that
it can be fight off infection.
01:56
So when these are healthy
my immune system is healthy
so ART should cause the
CD4 T-cell count to go up.
02:04
So if I see, I have a patient
I have their CD4 T-cell
count before treatment
if treatment is effective
the impact I should see is
their CD4 T-cell count going up.
02:16
Now we're assessing treatment from
the perspective of a viral load
this gives an
indication of the level
the numbers of HIV
virus in the body
ART should lower the viral load,
CD4 T-cell count should go up
that tells me immune
system is stronger
viral load should go down
and then we want to keep
it as low as possible.
02:39
So as a nurse when you're
checking the value awaiting
the effectiveness of therapy,
these are the 2 go to
test for someone on ART.
02:48
Now, how often do we test
will WHO the World
Health Organization
recommends a viral load
test every six months.
02:55
So you see on the calendar
we've got there for you,
6 right at we want
to at least 6 months
after you start
taking treatment.
03:03
So first test at six months
and then once a year,
so you're thinking about frequency
of testing for viral load
six months after treatment
got to give the medication
in the body time
to work together
and then once a year.
03:18
So help the patient pick a date
that means something to them.
03:22
Because effective treatment
means lower viral load
and it means a normal
CD4 T-cell count
or at least moving up there
but for effective treatment,
we want a normal
CD4 T-cell count.
03:35
So that means it's
going to be 500 or more.
03:40
So sometimes art
does stuff working
for many people in treatment,
they start taking will continue
to work as long as they take it.
03:49
Okay, so there's the key point,
for most people the treatment
will continue to be effective
if they continue to take it.
03:58
So as long as they
take it correctly,
then they should have
effective treatment
if something gets in their way
and stops them from doing that.
04:06
Remember the viral load
is going to go back up.
04:09
So if notice ART is
stopping working.
04:12
It's not working as much.
04:14
First of all,
how do we know that?
Right.
We look at those two tests.
04:18
We look the CD4 T-cell count
and we looked at viral load.
04:21
So now we see that the
CD4 T count is too low
and the viral load
is getting higher
so we know, this is not working.
04:30
So now we might thinking
we're going to think
through the possibilities.
04:34
I'm going to first find out
if they're able to be
compliant with timing
and taking it every day and
having the drug available.
04:41
We're also going to look at the
other medications they're taking
because another drug might be
having some type of interaction
with their medication
that could be the cause of
the ART to stop working.
04:51
So we might also
deal with patients
experiencing drug resistance.
04:55
Well, how does drug
resistance happen?
Think about how it happens
with antibiotics, right?
Patients don't finish a
complete prescription.
05:03
They take some, then they don't,
they take the wrong medication.
05:06
Well the same thing
happens with ART,
if they stop and start, stop and
start, and stop and start therapy
too much for their body.
05:14
They might be becoming
resistant to a drug.
05:17
So the healthcare provider can
help identify a different drug
that is likely to be effective.
05:22
That's the good news.
05:24
So what's our role?
Well, when we receive
the results that say
that ART is not working.
05:30
It's communication
with the patient.
05:31
Assess,
talk to them have a conversation
know in the back of your mind,
Hey, these are the reasons I
know that art stops working.
05:39
Most often most common.
05:41
These are the reasons
it stops working
have a non-judgmental
conversation with the patient,
gather data about other
medications that they're on
so when you speak with
the healthcare provider
you have complete information
for them to make the
next best decision.