00:01
Now, we're going to talk
about the urinary system
which has a very important role in filtering blood
as well as helping maintain blood pressure.
00:12
The workhorse of the urinary system are the kidneys
where the actual filtration of blood takes place.
00:18
And then, after it's been filtered,
that filtrate will be passed down the ureters,
down to the urinary bladder where
it's eventually expelled from the body.
00:29
Now, sometimes, when you see an anatomy book,
you see the abdomen open
and you just see kidneys sitting there
and that's not exactly how the kidneys sit.
00:37
In fact, they're actually behind that lining of the abdominal cavity
that we call the peritoneum.
00:45
Along with other structures.
00:47
So, we see other retroperitoneal things
such as the abdominal aorta and the inferior vena cava.
00:54
So, the kidney along with these other
structures are retroperitoneal
unlike a lot of the digestive structures that occupy
the majority of the peritoneal cavity itself.
01:04
The other thing that you don't really notice in a lot of pictures
is that the kidneys don't just sit there as kidneys.
01:11
They're surrounded by a lot of prerenal fat.
01:15
So, it actually takes a lot of effort to actually reach the kidneys
if you're going through the abdominal cavity
because, again, you'd have to
go passed the peritoneum
and generally, you would have
a lot of surrounding fat.
01:30
Let's talk a little bit about
the structure of a kidney,
so, the kidney is encased in a thin
but fairly tough renal capsule
and it has, like a lot of organs,
one spot where that capsule's
not present for things to enter
and exit called the renal hilum.
01:48
Hilum's a term that exists in a lot of organs
such as the spleen, the lungs, lymph nodes.
01:56
Anything that's generally solid
but has one entry and exit point.
02:02
The outer portion of the kidney that's called the cortex
and there's an inner portion called the medulla.
02:12
And again, those terms are pretty common for a lot of structures.
02:15
Cortex means bark like the bark of a tree.
02:18
So, cortex, whenever you see that, means
it's the sort of outer portion of an organ.
02:24
And the medulla's arranged into these
triangular-shaped things called pyramids
that are separated from each other by little columns
of cortex that come down in between them.
02:35
The tips of those pyramids point into the beginning
of what's called the collecting system
and that first portion of the collecting
system are called the calyces.
02:47
Before we talk about where that collecting system goes,
let's talk about how things enter and exit at this renal hilum.
02:57
So, eventually, food's going to exit out the ureters which are going to be the posterior-most structure of the hilum.
03:06
Then, just anterior to that will be the renal artery
which is going to branch and supply the kidney.
03:12
And then, more anterior to that is going to be
where the renal vein enter that renal hilum.
03:19
Okay. So, back to this collecting system.
03:23
So, if we zoom in a little bit, we again have the renal pyramid
which has a little tip at the end call the renal papilla
and it's through these little renal papilla that the very
beginnings of urine are going to drop out through
and they're going to drop into small little spaces called
minor calyces which will merge to form major calyces.
03:49
And then, all of the calyces together are going to mergeinto a single relatively large space called the renal pelvis.
04:00
The renal pelvis is going to drain into
the ureter at the renal hilum.
04:07
And so, this is an area where it's going to go from
very wide and broad to a fairly narrow tube.
04:12
So, we're going to see that that
has a lot of clinical significance.
04:15
For example, if a stone were to be floating around in the pelvis,
it might become lodged in the relatively narrow ureter.
04:25
So, in order to really understand the kidney,
we have to talk a little bit about the microanatomy
and we have to understand at least the concept of
what a nephron is and how blood is actually being filtered.
04:38
So, out in the cortex, there are these
little tuffs of capillaries called glomeruli
and that's where the blood is going to actually be filtered.
04:50
But it's not enough to just filter blood.
04:52
That filtered blood or filtrate or early beginnings
of urine need to be further modified,
so, it'll go through a long tube, initially,
a twisty tube called the proximal convoluted tubule
and then, a loop of Henle that actually
dips down into the medulla.
05:12
And then, another twisty part
called the distal convoluted tubule
before entering into a larger duct
called the collecting duct
which is really the last chance to modify filtrate,
usually, by either pulling out water
or letting more water in
because these collecting ducts
are eventually going to empty at the
renal papillae into the minor calyx
after which, it can't be modified any further.
It can just be passed all the way out the body as urine.
05:44
So, here, we have a close-up view of a very
small branch of the renal artery supplying
something called the afferent or afferent arteriole
that branches into a tuft of capillaries
and those are the glomerular capillaries
where filtration will take place.
06:02
And then, it will exit as the efferent
or efferent arteriole.
06:07
And surrounding this tuft of capillaries
is something called the glomerular capsule
which is a very special type of epithelium
that's going to interact very, very closely
with these capillaries to make sure that filtration
is only going to filter out the things
we want filtered out and not the things we want
to stay in the blood, for example, cells and proteins.
06:31
That filtration will then work its way down through
all of these tubules and collecting duct
and be further modified by either tubular reabsorption
or secreting things back out into the tubules.