Adverse Effects/Contraindications/Side Effects/Interactions

by Diana Shenefield, PhD

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    Today we're going to talk about adverse effects, contraindication, side effects, and interactions of pharmacological meds again. So, we've talked about what are expected. Now, we're talking about all of the things that are either expected but aren't good or unexpected. My name is Diana Shenefield. Let's get started. Again, why do we need to know this? Because on NCLEX, you need to know your medications, not only why they're given, but you need to be prepared for side effects, adverse effects, and any other contraindications that might be going on with the patient. One, so that I can be watching forward as the nurse, but two, so that the patient can be educated on what to watch for at home. Look at your learning outcomes. Make sure that you understand each one of the outcomes and make sure that you're prepared educationally to answer any questions that deal with those outcomes. If you have questions, make sure you'd go back to your pharmacology book, and make sure you'd go to your NCLEX review books. So, we're going to start with a question to get you thinking. A patient is admitted for pulmonary embolism, receives heparin 1500 units per hour IV. In case of a serious bleeding reaction, what are you going to give? You need to know antidotes. You need to know antidotes of all your medications, especially the ones that can be life-threatening. And we know bleeding from heparin can be life threatening. So, what are you going to give? Are you going to give vitamin K? Are you going to give protamine sulfate? Are you going to give promethazine? Or are you going to give protamine? So think back to your heparin and what is the antidote? And hopefully, you picked protamine sulfate. Again, if you can't...

    About the Lecture

    The lecture Adverse Effects/Contraindications/Side Effects/Interactions by Diana Shenefield, PhD is from the course Physiological Integrity. It contains the following chapters:

    • Review of Unintended Responses to Medications
    • Side Effects and Adverse Medication Effects
    • Toxicity and Allergic Reactions
    • Iatrogenic, Teratogenic and Carcinogenic
    • Medication Interactions

    Included Quiz Questions

    1. Tachycardia
    2. Bradycardia
    3. Lethargy
    4. Tachypnea
    1. Nausea and vomiting
    2. Patient complains of decreased hearing or hearing loss
    3. Elevation of serum BUN and/or creatinine
    4. Urine output of less than 600 ml daily
    1. To reduce side effects of the Thorazine
    2. To decrease the incidence of seizures
    3. To potentiate the action of Thorazine
    4. To improve and stabilize mood
    1. Evaluate patient’s intake of grapefruit juice
    2. Assess for evaluation of body temperature
    3. Evaluate rate, depth, and regularity of respirations
    4. Assess for weight loss by obtaining a daily weight
    1. “This is an expected side effect of the drug, and you should use caution and move slowly when standing up.”
    2. “You may be experiencing a toxic effect of the drug, and I will notify the physician”
    3. “Dizziness is not related to the drug, but I will need to ask you a few more questions.”(
    4. “Episodes of dizziness when moving are common symptoms of elevated blood pressure.”

    Author of lecture Adverse Effects/Contraindications/Side Effects/Interactions

     Diana Shenefield, PhD

    Diana Shenefield, PhD

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