00:01
Why are we talking about an Addisonian crisis?
Well, Nurse Natalie's probably
expressing your frustration right there.
00:07
But I want to reinforce the most likely time
you're going to see an Addisonian-like crisis
is when a patient who has been on higher dose
steroids for a fairly long period of time,
they've experienced adrenal gland suppression
because they've been on those
corticosteroids for a long period of time.
00:25
And now, for some reason, either we fail to give
them to them, or they decided to stop taking them --
boom!
We throw them right into an Addisonian crisis.
00:36
Their adrenal gland starts acting like
someone who has Addison's disease
because it's been suppressed with the therapy.
00:43
And unless you wean the patient
off that medication slowly,
you throw them straight
into an Addisonian crisis.
00:51
Remember, the Sugar Daddy Syndrome.
00:54
That adrenal gland gets real comfortable,
because it's not getting stimulated at all.
00:58
And if you abruptly stop
corticosteroid therapy,
you'll see the same symptoms that we would
see with someone in Addison's disease
who's not receiving enough
hormone replacement therapy.
01:10
So, let's --
I want to see what you can come up with.
01:14
You already know Cushing's, we've
discussed that and you've reviewed that.
01:17
And I've let you know that in
Addisonian crisis, the side effects,
when you have a real shortage,
are going to be the opposite
of what you see in Cushing's.
01:25
So before we walk through
these, let's have some fun.
01:28
Let's see what you can remember and
apply to an Addisonian crisis,
the opposite of what you see in Cushing's disease.
01:44
All right.
01:45
Now, we just put a lot of the symptoms up there.
01:48
Because they're dehydrated,
you're going to see the fever.
01:51
You're going to see this electrolyte
imbalance with that salt,
so they're going to be weak and kind of confused
because that's how patients act
when they have low sodium.
02:00
Your blood pressure is going to be low.
02:03
And we've got the word "postural"
there to remind you, that man,
when these people stand up, they're
really going to get dizzy.
02:10
Why do you have that fast heart rate?
Because you have low volume,
blood pressure has dropped,
and that's a compensatory mechanism by the body.
02:18
You have that low volume
because you're dehydrated.
02:21
You don't have enough of that aldosterone
available from the adrenal cortex.
02:25
Now, low sodium, higher potassium, which is again,
the exact opposite of what we saw in Cushing's.
02:33
Blood sugar also going to be low.
02:35
So look at these guys as a total picture.
02:39
Addisonian crisis.
02:40
It happens in disease, when we don't
have good replacement therapy.
02:44
It happens in our patients
receiving corticosteroids
or people who have Cushing syndrome
when, for some reason, they don't
receive their medication either.
02:55
Both cases we have adrenal
glands that can't function.
02:58
In Addison's disease, it's usually because it's an
autoimmune disorder that knocked out the organ.
03:03
In Cushing syndrome, it's because they
abruptly stopped taking their medication.
03:09
So how do we fix an Addisonian crisis?
Whether it's from Addison's disease, or
it's from somebody with Cushing syndrome
who stopped taking their medications, I
want you to watch for the signs of crisis.
03:20
Now, let's go back and look at that
other slide for just a minute.
03:25
What are the biggest problems we have here?
Well, let's start on the right side.
03:29
You've got fever.
03:31
Okay, well, I can give you Tylenol for that.
03:33
That's okay.
03:35
I've got low blood pressure
because I've gotten dehydrated.
03:39
All right, well, I could give
you some IV fluids for that.
03:43
I could probably address that.
03:45
Maybe deal with your sodium, and your blood sugar,
I can give you some high carb
food if you can swallow.
03:50
Yeah, none of that is going to
work until you do this next thing.
03:56
You have to replace the hormones.
03:59
You are just trying to fix a problem that you
will never fix until you replace those hormones.
04:06
You need to, most importantly, replace those
hormones and do all that other stuff.
04:11
It'll fall into place if we can replace
the hormones and provide rehydration
and deal with their fever,
things will come back to normal.
04:20
Always make sure that you taper steroids
and you teach your patients the importance
of that, versus just abruptly --
stopping them 1 day.
04:29
Remember, a patient with an adrenal
gland that has been suppressed,
if they go through stressors in their
life, like, I don't know, nursing school,
or moving, or divorce, or death, or
marriage, you never know what it is.
04:44
They might need some extra steroids
to deal with those cycles.
04:49
They might need some extra steroids
to deal with those stressors.
04:53
And don't rule out psychosocial things
or physical events or pregnancy.
04:58
Stress is what your patient perceives it to be.
05:02
All right.
05:03
1 more chance for you to see how you're doing.
05:05
You supercharge your memory.
05:06
This is a great exercise.
05:09
Don't look at your notes.
05:12
What you want to do is see, list from head to toe,
the symptoms of Cushing's and on the other
side, list the symptoms of Addison's.
05:20
Keep in mind they're exact opposites
or mere images of each other.
05:26
Ready?