Pathology III advances students’ understanding of disease processes by focusing on disorders of the endocrine and reproductive systems, along with comprehensive coverage of hematologic abnormalities and oncologic principles. This integrative course examines the complex interrelationships between hormonal dysregulation, reproductive dysfunction, hematopoietic disorders, and neoplastic transformation. Students will investigate the molecular mechanisms, histopathological features, and clinical manifestations of diseases affecting the pituitary, thyroid, parathyroid, adrenal glands, pancreatic islets, male and female reproductive organs, bone marrow, and lymphoid tissues.
By synthesizing knowledge of cellular pathology, molecular biology, and clinical medicine, students will gain a comprehensive foundation in endocrine, reproductive, and hematologic pathology essential for medical practice, particularly in specialties dealing with hormonal disorders, reproductive health, and oncological conditions.
Learning objectives
After the completion of this course, you will be able to:
- Analyze the pathophysiologic mechanisms underlying disorders of the hypothalamic-pituitary axis, thyroid, parathyroid, and adrenal glands, correlating hormonal imbalances with their clinical manifestations.
- Evaluate the pathogenesis of pancreatic endocrine disorders, including diabetes mellitus, with emphasis on molecular mechanisms and systemic complications.
- Differentiate between benign and malignant neoplasms of endocrine organs based on their morphological features, molecular profiles, and biological behavior.
- Analyze the pathological processes affecting the female reproductive system, including disorders of the ovaries, fallopian tubes, uterus, cervix, and breast.
- Characterize pathological conditions of the male reproductive system, including inflammatory, developmental, and neoplastic disorders of the prostate, testes, and external genitalia.
- Interpret the morphological and functional alterations in hematopoietic disorders, including anemias, leukemias, myelodysplastic syndromes, and myeloproliferative neoplasms.
- Evaluate the pathophysiology of lymphoid neoplasms, including lymphomas and plasma cell dyscrasias, based on their histological features and molecular characteristics.
- Integrate clinical, laboratory, and pathological findings to formulate comprehensive assessments of endocrine, reproductive, and hematologic disorders.
- Assess the impact of modern diagnostic methodologies, including molecular and immunohistochemical techniques, on the classification and therapeutic approach to endocrine, reproductive, and hematologic malignancies.
Course outline
- Endocrine Pathology
- Reproductive Pathology
- Hematology and Oncology
