Urea Cycle
About the Lecture
The lecture Urea Cycle by Kevin Ahern, PhD is from the course Amino Acid Metabolism.
Included Quiz Questions
Which of the following is true regarding the urea cycle?
- Two amines are used in the reaction that forms urea.
- It primarily occurs in the muscles.
- It generates ATP.
- Water is not needed for the reaction to occur.
- It outputs 3 amines per turn of the cycle.
Which of the following is NOT true of the urea cycle?
- The urea cycle takes place in the neuronal cells to get rid of the toxic effect of ammonium ions produced during amino acid catabolism.
- One urea molecule is produced per turn of the urea cycle.
- The urea cycle occurs in the cytoplasm and mitochondria of the liver and kidney cells.
- The net reaction for the urea cycle is 2NH3 + CO2 + 3ATP + H2O → CO(NH2)2 + 2ADP + 4Pi + AMP.
- In the urea cycle, the feeder reaction synthesizes the carbamoyl phosphate by incorporating ammonium and bicarbonate ions with the help of carbamoyl phosphate synthetase.
Which of the following is not correctly matched regarding the reactions and enzymes in the urea cycle?
- Ammonium ion + bicarbonate ion → carbamoyl phosphate — ornithine transcarbamoylase
- Carbamoyl phosphate + ornithine → citrulline — ornithine transcarbamoylase
- Citrulline + ATP + asparate → argininosuccinate + AMP + 2Pi — argininosuccinate synthetase
- Argininosuccinate → arginine + fumarate — argininosuccinate lyase
- Arginine + water → urea — arginase
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Author of lecture Urea Cycle
Kevin Ahern, PhD
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After Biochem, I feel like myself a reborn
By Jerry J. on 03. April 2018 for Urea Cycle
Wow, these two amines are very tricky, thank you very much, Prof. Ahern!
