Pharmacology Question Set 5

by Lecturio USMLE

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    About the Lecture

    The lecture Pharmacology Question Set 5 by Lecturio USMLE is from the course Pharmacology - High Yield Questions.

    Included Quiz Questions

    1. Propranolol
    2. Sumatriptan
    3. Verapamil
    4. Ergotamine
    5. Valproic
    1. Inhibits cyclooxygenase pathway
    2. Inhibits lipoxygenase pathway
    3. Inhibits sodium voltage gated channels
    4. Inhibits calcium voltage gated channels
    5. Potentiates action of GABA
    1. Syndrome of inappropriate ADH
    2. Gingival hyperplasia
    3. Hirsutism
    4. Alopecia
    5. Pinpoint pupils
    1. Clindamycin
    2. Cefuroxime
    3. Cefotetan
    4. Oral vancomycin
    5. Aztreonam
    1. Inhibits voltage gated calcium channels
    2. Inhibits voltage gated sodium channels
    3. Potentiates GABA transmission
    4. Inhibits neuronal GABA receptors
    5. Inhibits release of excitatory amino acid glutamate
    1. It suppresses the ciliary epithelium from producing aqueous humor
    2. Increased outflow via dilatation of the uveoscleral veins
    3. It leads to opening of the trabecular meshwork
    4. It decreases the production of aqueous humor by decreasing levels of bicarbonate through cAMP mediated pathway
    5. It increases the transit of aqueous humor into the vitreous humor for absorption into the choroid
    1. To compensate for warfarin’s initial prothrombotic property
    2. To achieve supraoptimal anticoagulation during critical periods of illness as warfarin and heparin have synergistic effects
    3. To prevent bleeding as heparin partially counteracts warfarin’s hemorrhagic property
    4. Warfarin is metabolized slowly thus leading to a delay in anticoagulation if heparin is not also given.
    5. Heparin decreases the clearance of warfarin thus achieving greater plasma drug concentration of warfarin
    1. It has no direct effect on cardiac muscle
    2. It can be used along with PDE inhibitors compared to other forms of nitroglycerin
    3. It has similar mechanism of action with nitroprusside by phosphorylation of myosin light chain phosphate
    4. The primary mechanism for decrease in BP is due to decrease in afterload
    5. It decreases heart rate and thus decreases cardiac workload
    1. Guanosine analog that preferably inhibits viral DNA polymerase
    2. Inhibits A-site tRNA binding during translocation
    3. Blocks CCR5 receptor preventing viral entry
    4. A neuraminidase inhibitor preventing release of viral progeny
    5. Prevents viral uncoating
    1. Metoprolol
    2. Furosemide
    3. Digoxin
    4. Dobutamine
    5. Nesiritide
    1. Clozapine
    2. Haloperidol
    3. Quetiapine
    4. Risperidone
    5. Olanzapine
    1. There is increased risk of gallstone formation when fibrates are combined with bile acid binding resins.
    2. Simvastatin, a reversible inhibitor of HMG-CoA synthase is most effective in reducing LDL levels.
    3. Niacin stimulates PPAR-α causing an increase in HDL and a decrease in triglycerides.
    4. Ezetimibe inhibits production if bile acids thus decreasing cholesterol utilization.
    5. HMG CoA-reductase inhibitors produce constipation as their major side effect.
    1. Phase 2
    2. Phase 0
    3. Phase 1
    4. Phase 3
    5. Phase 4
    1. Pyrazinamide
    2. Rifampicin
    3. Isoniazid
    4. Ethambutol
    5. Streptomycin
    1. Leuprolide
    2. Mestranol
    3. Anastrazole
    4. Danazol
    5. Clomiphene
    1. Succinylcholine is an example of a depolarizing neuromuscular blocker because of its strong Ach antagonistic activity.
    2. There are two types of neuromuscular blocking drugs classified as either depolarizing or non-depolarizing.
    3. Tubocurarine, atracurium, and rocuronium are examples of non-depolarizing neuromuscular blockers.
    4. Neostigmine is used as an antidote for non-depolarizing neuromuscular blockers.
    5. Complications of depolarizing neuromuscular blockers include hypercalcemia, hyperkalemia, and malignant hyperthermia.
    1. Dependence and addictive CNS depression effects with alcohol can occur
    2. It facilitates GABA-A action by increasing duration of Cl- channel opening, thus decreasing neuron firing
    3. Benzodazepine overdose is treated supportively assisting in respiration and vital signs support
    4. Most benzodiazepines such as midazolam and triazolam have long half lives and active metabolites
    5. Zolpidem is a unique benzodiazepine used for insomnia as it acts by binding on the GABA-A receptor and facilitates sleep
    1. Tyrosine kinase inhibitor of bcr-abl and c-kit
    2. Monoclonal antibody against HER-2 (c-erbB2),a tyrosine kinase receptor
    3. Monoclonal antibody against CD20
    4. Monoclonal antibody against VEGF
    5. Small molecule inhibitor of forms of the B-Raf kinase with the V600E mutation
    1. Triamterene
    2. Eplerenone
    3. Furosemide
    4. Acetazolamide
    5. Hydrochlorothiazide
    1. Thalamic T-type Ca2+ channels
    2. Na+ channel
    3. GABA-A receptors
    4. High voltage- activated Ca2+ channels
    5. BZ1 subtype of the GABA receptor

    Author of lecture Pharmacology Question Set 5

     Lecturio USMLE

    Lecturio USMLE

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