Pathology Question Set 12

by Lecturio USMLE

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    About the Lecture

    The lecture Pathology Question Set 12 by Lecturio USMLE is from the course Pathology - High Yield Questions.

    Included Quiz Questions

    1. The gene locus which is mutated in this condition is on chromosome 9.
    2. The condition is inherited as autosomal dominant condition.
    3. Gait ataxia in this condition is a pure sensory ataxia.
    4. Vertical nystagmus is characteristically seen in patients suffering from this condition.
    5. Restrictive cardiomyopathy is seen in approximately 50% of the patients.
    1. Gene for mitogen-activated protein (MAP) kinase phosphatase-1 is activated by inhaled corticosteroids, which produces anti-inflammatory effects.
    2. β2-agonists reverse bronchoconstriction but do not control underlying inflammation because inflammatory cells do not express β2 adrenergic receptors.
    3. Theophylline activates histone acetyltransferase and therefore exerts anti-inflammatory activity in bronchial asthma.
    4. Antileukotrienes exert their beneficial effects in bronchial asthma by blocking cys-LT2-receptors.
    5. Omalizumab acts by blocking both circulating IgE and cell-bound IgE to produce therapeutic effects in bronchial asthma.
    1. In patients with high-level nasal resistance, the opening of mouth during sleep prevents apnea/hypopnea episodes.
    2. Most common site of collapse of pharyngeal airway during sleep apnea is at level of base of tongue.
    3. Overnight blood pressure monitoring in the patient may not show a fall during sleep from blood pressure while awake.
    4. Episodes of apnea and hypopnea are more likely to occur during deeper stages of non-rapid eye movement (NREM) sleep.
    5. Gynoid obesity is associated with apnea and hypopnea more frequently as compared to android obesity.
    1. Mucosal atrophy
    2. Increased number of intraepithelial lymphocytes
    3. Crypt hyperplasia
    4. Reduced height of villi
    5. Cuboidal appearance of surface epithelial cells
    1. Anti-CRMP5
    2. Anti-Hu
    3. Anti-Ri
    4. Anti-amphiphysin
    5. Anti-Yo

    Author of lecture Pathology Question Set 12

     Lecturio USMLE

    Lecturio USMLE

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