Lectures

Sarcoidosis

by Carlo Raj, MD
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    About the Lecture

    The lecture Sarcoidosis by Carlo Raj, MD is from the course Restrictive Lung Disease. It contains the following chapters:

    • Sarcoidosis
    • Pathogenesis
    • Diagnosis

    Included Quiz Questions

    1. Mediterranean descent
    2. Young patients
    3. Scandinavians
    4. African Americans
    5. Women
    1. Blepharochalasis
    2. Hilar adenopathy
    3. Acute onset of fever
    4. Erythema nodosum
    5. Polyarthritis
    1. Caseating granuloma on biopsy
    2. Hilar adenopathy on CXR
    3. Neurological symptoms
    4. Polyarthritis
    5. Restrictive lung disease
    1. Total lung capacity is usually increased.
    2. It may involve inflammation of subcutaneous fat on the lower limbs.
    3. Forced expiratory volume is decreased less than forced vital capacity.
    4. It is often diagnosed incidentally on CXR while patient is asymptomatic
    5. It is idiopathic and there are no known effective prevention strategies.
    1. All of the answers would be expected to be elevated.
    2. Serum phosphate levels
    3. Vitamin D levels
    4. Serum calcium levels
    5. Serum ACE levels
    1. At least 3 multinucleated giant cells must be found with negative cultures.
    2. At least 1 multinucleated giant cell with regions of friable cellular debris and necrosis.
    3. At least 3 multinucleated giant cells with regions of friable cellular debris and regions with acellular ghost cells.
    4. At least 1 multinucleated giant cell infiltrating a preformed cavitary space.
    5. At least 3 multinucleated giant cells surrounding angle branching, septate hyphae.
    1. Asymptomatic patients should be treated with corticosteroids to avoid progression of disease.
    2. Patients diagnosed incidentally by CXR should be observed.
    3. Many patients’ conditions improve spontaneously.
    4. Persistent disease that is steroid refractory is an indication for anti-TNF therapy.
    5. Symptomatic disease is often treated with systemic corticosteroids.

    Author of lecture Sarcoidosis

     Carlo Raj, MD

    Carlo Raj, MD


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